According to the hitherto Neglected sources of Nuṣ ayriyah in Syria, Muhammad Ibn Ebrahim al-Katib al-Nu'mani was a well-known figure among them. In addition to reports of his relationship with the great men of Nusayriyah, such as Khasibi, Jelli, Ibn Shu'ba, Qati'i Baghdadi, Ghasani Mohlahali, etc The compilation of several books (Al-Ikhlas, Al-Muqne', Al-Thassilya and Altaqwa and. . . ) is attributed to him. And of course, among reports and sayings narrated from him, in addition to the correct subjects, there are many incredible opinions and narrating of the extremist and metempsychosis book "as-Sab'in". The Evidences of his governmental post are more obvious in the books of Nusayriyah too. It is noteworthy that these abundant reports, despite its weakness, also have some witnesses in Imamyh's sources; the most important of them, which is the narrator of the book Al-Ghaibah is Nusayri. Yet, beyond his relationship with the Nusayriy sect, there is no solid proof that confirm the Nusayri reports about his corrupt Extremist opinions. So that his narrations in Imamy's sources generally do not have a clear connection with the formal beliefs of Extremist shiites.

The concept of documentation in management and particularly, in project management, is different from the concept of this term from knowledge management perspective. What considered in this research is knowledge management perspective and the Neglected loop of knowledge management at research centers and institutes in order to use experiences of heads and deputies at research centers and institutes. In documenting from the viewpoints of knowledge management, each decision, event, and effective activity the organization, which includes the explicit and implicit knowledge of the organization, has the value for documentation. Therefore, it includes assessment of the decisions and actions taken and, through the gathered knowledge and information it will provide a suitable basis for assessing these actions. Also, if we consider research centers and institutes as a center with financial and human resources, including faculty, staff and students in which knowledge sharing and dissemination are addressed, two important issues get attention. First, the capital role of the research centers and institutes that are well-defined and of interest for community and the state. Because research centers and institutes are considered as institutions for the production, improvement and development of knowledge in different fields, and in our country, due to existence of various research centers and institutes, this mission has been considered and every year, a huge amount of money is spent on trial and error for decision-making by directors and managers of research centers and institutes. Second, knowledge management process consists of producing or collecting and identifying knowledge, categorizing, storing and documenting knowledge, distributing and disseminating knowledge and applying knowledge, which is one of the main missions of universities and research centers and institutes. This study shows that the process of documenting of management experiences follows a three-step process including: planning of documentation, implementation of documentation, monitoring, control, and sharing.

Dear Editor The outbreak of Covid-19 has caused concern among the general population around the world. Many people may be anxious and scared, and those who are directly affected by the virus in different ways may experience more panic, fear, and anxiety [1]. Everyone who is exposed to a traumatic crisis is affected to varying degrees [2]. The effects of an accident crisis on some people go away quickly, and they regain resilience. However, typically at least one-third of these people develop a condition called Calamity Syndrome,that is, the patient may be physically relieved of the disease over time, but its psychological effects may remain in him/her for a long time [3]. But the question is, which groups are most at risk for Calamity Syndrome, which includes severe anxiety, stress, and thought disorders?..

Purpose: Here, we aim to evaluate the antileishmanial activity of compounds with a benzoxazinoid (BX) skeleton, previously synthesized by our group, against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) infantum promastigotes. Methods: Anti-promastigote activity, as well as cytotoxicity, were determined using the 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) colorimetric assays. The selectivity index (SI) for each compound was calculated using a ratio of the cytotoxicity of compounds and the geometric mean (GM) of antileishmanial concentrations to each species tested. The comparisons between groups were carried out using a t test or analysis of variance (one-way ANOVA). A P value of less than 0. 05 was considered significant. Results: All the compounds tested were active, with IC50 falling between 92 ± 6. 19 μ g/mL and 238± 6. 57 μ g/mL for L. braziliensis, and 89 ± 6. 43 μ g/mL and 188 ± 3. 58 μ g/mL against L. infantum. Bex2, Bex3, Pyr1, Pyr2, and Pyr4 were compounds that showed activity similar to the drug Glucantime® , exhibited low cytotoxicity against splenic hamster cells (CC50 raging between >400 and 105. 7± 2. 26 μ g/mL) and had favorable selectivity indices (SI 1. 12 to 3. 96). Conclusion: The analogs in question are promising prototypes for the pharmaceutical development of novel, safer and more effective leishmanicidal agents.

The incidence and prevalence of diabetes mellitus and its complications are increasing. Like other complications, most of the diabetes patients have gastrointestinal (GI) symptoms but in majority of cases GI complications are under diagnosed and not treated properly, resulting in impairment of the quality of daily life. GI system including liver and pancreas are involved in diabetes mellitus. These GI complications of diabetes mellitus need proper diagnosis and treatment to get a quality of life and clinician needs clinical suspicion to identify and proper knowledge to treat.

Leishmaniasis is an endemic parasitic disease in Iran. This paper reports the case of a 5-yr-old boy who presented with multiple isolated cervical lymphadenopathy for several months with no history of fever and no signs or symptoms. In an excisional lymph node biopsy, Leishmania parasites were histologically detected. Thus, leishmaniasis should be included in the differential diagnosis of isolated lymphadenitis in immunocompetent patients, even if the K39 and IFA for kala-azar are reported as negative.