Familial cardiac Myxoma is a rare syndrome which constitutes approximately 10% or less of all Myxomas. We describe a rare case of a simultaneous left atrial and left ventricular mass in a 35- year-old female who presented to our hospital for the evaluation of recurrent cardiac Myxoma. Echocardiography revealed a concurrent left atrial and left ventricular mass. Histological findings after surgery confirmed the diagnosis of Myxoma

We report a case with a left atrial mass who underwent coronary angiography to rule out coronary artery disease. Coronary angiography revealed an anomalous tortuous vascular structure originating from the left circumflex coronary artery to the left atrial tumor suggestive of neovascularization. Preoperative coronary angiography is useful for coronary artery evaluation and also provides additional information regarding the feeding vessel supplying the mass.

Introduction: Myxomas are benign mesenchymal neoplasms which arise mainly in the heart. The laryngeal localization is very rare. We aim to describe the clinical, histological and therapeutic features of this condition. Case Report: We report two cases of laryngeal Myxomas occurred in male and female patients, presenting with a history of prolonged hoarseness. Laryngoscopy revealed a polypoid mass on the true vocal folds. The lesions were excised with cold instruments. One patient presented a recurrence 4 years after the first surgery. Conclusions: Laryngeal Myxoma should be considered in case of a benign looking vocal fold lesion, especially a vocal cord polyp. Histologic exam is the only tool to confirm the diagnosis. It is treated by surgical resection. In the literature, recurrence is rare in laryngeal site, but patients need to be kept on close follow-up.

Odontogenic Myxoma is a benign mesenchymal tumor that appears to be associated with odontogenic ectomesenchyme of the growing teeth. This tumor, which often occurs in the second and third decades of life, is extremely rare and often asymptomatic in children. However, no theoretical consensus exists in the literature over the diagnosis and treatment of this disease. In this study, we investigated the diagnostic and therapeutic methods of a rare case of odontogenic Myxoma in a 13-year-old child.

Primary heart tumors are not common. Although Myxoma is the most common tumor of the heart, mitral valve Myxoma is extremely rare. The patient is a 55 years old woman who had atypical retrosternal pain, retinal artery emboli and visual deficit. In transesophageal echocardiography a (4x3x3) cm mass was detected in posterior leaflet of mitral valve. The posterior leaflet of mitral valve was totally resected and the mitral valve was successfully replaced with prosthetic mechanical valve. Histopathology result confirmed Myxoma.

Myxoma is the most common type of primary tumors of the heart. It is a rare tumor with an estimated incidence of 0.5 per million populations per year. Most cardiac Myxomas originate in the atrial septum in the area of the fossa ovalis and 75% occur in the left atrium. Valvular Myxomas are very rare: the tricuspid valve is the most frequently involved location, followed by the mitral, pulmonic, and aortic valves.Our case was a 24-year-old male with mitral valve Myxoma and a history of progressive dyspnea.After diagnosis was confirmed by 2-dimensional echocardiography, he underwent cardiac surgery, the tumor was successfully excised from the posterior leaflet of the mitral valve, and the mitral valve defect was repaired with direct suture.  

Cardiac Myxomas are the most common primary cardiac tumors, with an estimated incidence of 0. 5 per million individuals annually. Although surgical resection is curative however, postoperative tumor recurrence has been reported, especially in familial and complex type of Myxoma. Literature reviews reveal only a few cases of recurrence in sporadic cardiac Myxoma. Herein we have reported a case of sporadic cardiac Myxoma, with multiple recurrences after surgical resection. The possibility of repeated recurrence of cardiac Myxomas demonstrates the importance of regular echocardiographic surveillance after surgical resection in order to detection of recurrence even in non-familial and non-syndromic cases. Further evaluations, including genetic analysis of patients with recurrent cardiac Myxomas, are warranted to investigate the exact nature of these tumors.

Introduction: This is a report of the histopathological characteristics of a rare case of primary adrenal Myxoma. A 25-year-old male was admitted to AI-Zahra Hospital due to abdominal trauma. Radiological evaluations revealed an adrenal mass without any clinical manifestation. The MRI of abdomen showed a well-defined cystic mass of right adrenal with the following differential diagnoses: cystic adenoma, cystic pheochromocytoma and metastatic lesions with cystic degeneration. Right adrenalectomy was performed and in pathologic study, the mass was grossly solid and had yellow-grayish color and gelatinous consistency in cut surface. Microscopically, it was composed of myxoid stroma with few scattered cells which were positive for vimentin but negative for CK, CEA, S100, Desmin, Actin and Melan-A in immunohistochemical staining. These findings are characteristic of primary adrenal Myxoma.Discussion: Pathologically, it may be difficult to differentiate Myxoma from other malignant tumors with a myxoid stroma. Further studies are necessary to clarify the origin and histogenesis of this lesion.

Nerve sheath Myxoma has been described as a rare neural tumor arising from Schwann cells. It is observed most frequently in the central area of the face, neck and upper extremities. In the past the term neurothekeoma was used as synonym for nerve sheath Myxoma but according to new reports, they are separate entities which can be confirmed by immunohistochemistry as in our case. Oral involvement of this tumor is extremely rare. Here, we present an unusual case of nerve sheath Myxoma in the mandible of a 22-year old female patient. This case appears to be the first Myxomatous variant which is centrally located in the mandible.

Although cardiac tumor is rare, cardiac Myxoma is the most common primary cardiac tumor in adults (50%- 70%). Myxoma, as a benign neoplasm, can develop in any chamber of the heart; the most commonsite being the left atrium (75%) with an overall incidence of about 0.5/million/year. Nowadays echocardiography plays a crucial role in early precise diagnosis and treatment and, therefore, prevents life- threatening complications. Occurrence of cardiac Myxoma with valve origin, particularly in the right atrium has rarely been reported worldwide (fewer than 10 cases). In this report, we present a young patient that was admitted to the hospital with pleuritic chest pain due to right pulmonary embolization and infarction and the unusual finding of septal leaflet of tricuspid valve origin of tumor with invasion of villous lesions to the right ventricle.