The Objective of this research was determination of antioxidant and antimicrobial activities of different plants of the families lamiaceae including several salvia species and some plants of the family Compositae e.g. Onopordon, Centaurea from Iran. The radical scavenging activities of the above-mentioned plants were measured spectrophotometrically using DPPH (2, 2 dipheny-pycryl-hydrazyl). The antimicrobial tests were performed on an acetone extract of the plant material. The microorganisms applied for the bioassays were Bacillus subtilis and Escherichia coli as Gram positive and Gram negative bacteria respectively. The fungi were Cladesporium herbarum and Fusarium oxysporum. Our research on about 50 different plants showed Salvia choloroleucca, Salvia hypoleuca, and Salvia sahandica as the most potent antimicrobial plants. Our assays to separate the active constituents are continuing by TLC bioautography. We have determined different active plants amongst several candidates and studied them for further purification and identification by bioassay guided fractionation

Drug-induced nephrotoxicity is one of the most common causes of acute kidney injury. There are various agents that exert nephrotoxic effects through different pathogenic mechanisms. Aminoglycoside antibiotics, chemotherapeutic agents, radiocontrast media, and nonsteroidal anti-inflammatory drugs are among common nephrotoxic agents. In recent years, natural compounds are being increasingly used in the treatment of kidney diseases. Given many reports available on the curative effects of a variety of Medicinal plants against drug-associated nephrotoxicity, we aimed to review the protective effects of Medicinal plants on certain nephrotoxic drugs.