In this paper, we studied the effect of electron beam irradiation on the fabric to increase LONGEVITY of antibacterial coating and perfume release and measure it using the optical properties of the fabric. In other words, instead of using chemical compounds in the antibacterial coating and perfume structure, the change in the structural properties of the fabric as a substrate of antibacterial coating and perfume was examined. Three different types of fabrics, including fabric with polyester and cotton, fabric with felt and flannelette, and fabric with flannelette and cotton floss were irradiated at different doses without alcohol and in the presence of alcohol (96% ethanol) at an energy of 10 MeV with an electron beam of the Rhodotron accelerator TT200. Then, these three types of fabrics were impregnated with antibacterial coating and perfume after washing with cold water. Finally, the LONGEVITY of antibacterial coating and perfume on them was measured by using the Particle Density Reflection Parameters and He-Ne laser with a wavelength of 632 nm and a power of 5 mW. Experimental results showed that electron beam irradiation of the fabric in the presence of alcohol enhanced this property.

Background: We attempt to identify specific differentially methylated and expressed genes in people with LONGEVITY family history, it will contribute to discover significant features about human LONGEVITY. Methods: A prevalence study was conducted during October 2017 to January 2019 in Bama County of Guangxi, China and individuals were recruited and grouped into LONGEVITY family (n=60) and non-LONGEVITY family (n=60) to identify differentially methylated genes (DMGs). The expression profile dataset GSE16717 was downloaded from the GEO database in which individuals were divided into 3 groups, namely LONGEVITY (n=50), LONGEVITY offspring (n=50) and control (n=50) for identifying differentially expressed genes (DEGs). It was considered significantly different when P or adjusted P 0. 05. Results: In total, 117 LONGEVITY-related hypermethylated genes enriched in interleukin secretion/production regula-tion, chemokine signaling pathway and natural killer cell-mediated cytotoxicity. Another 296 significant key LONGEVITY-related DEGs primarily involved in protein binding, nucleus, cytoplasm, T cell receptor signaling pathway and Meta-bolic pathway, H19 and PFKFB4 were found to be both methylated and downregulated in people with LONGEVITY fam-ily history. Conclusion: Human LONGEVITY-specific genes involve in many immunity regulations and cellular immunity pathways, H19 and PFKFB4 show hypermethylated and suppressed status in people with LONGEVITY family history and might serve as LONGEVITY candidate genes.