Even though development of industry increases economic growth, it reduces the quality of the environment due to higher pollution coefficients. Therefore, creating an optimal structure for the industry to reduce the negative externalities is of great importance. Accordingly, by using the statistical evidence of selected countries for the period 2010-2017, and applying a spatial econometrics approach, this study investigates the effect of industrial AGGLOMERATION on entropy index as pollution AGGLOMERATION. The results show that there are spatial effects of pollutant emissions among the studied countries,also, the AGGLOMERATION of the industry reduces the AGGLOMERATION of pollutants due to the advantage of the spillover effect of knowledge and technology, and matching skills with jobs. In addition, the intensity of energy consumption increases the AGGLOMERATION of pollution. Moreover, regarding the relationship between GDP and pollution AGGLOMERATION, the Kuznets curve is confirmed indicating a nonlinear relationship between the two variables. Ultimately, the openness of economy in neighboring countries leads to reduction in pollution AGGLOMERATION, due to the effects of spatial spillover.