Background: Migraine and IRRITABLE BOWEL SYNDROME (IBS) are chronic conditions that seem to share common pathophysiological aspects.Objectives: Our study aimed to estimate the prevalence of IBS in an Iranian migraine population, investigate its association with headache's characteristics and depression.Materials and Methods: This cross-sectional study was done in a tertiary hospital clinic in Iran. Of patients referring for headache, migraineurs were diagnosed using international classification of headache disorder second edition (ICHD-II) by an experienced neurologist. Then, they were asked to answer to IBS section of SEPAHAN (The study on the epidemiology of psychological, alimentary health and nutrition) questionnaire, Persian version of Rome III questionnaire, to identify IBS and its subtypes in patients. Depression was evaluated by using Persian version of Beck-Depression Inventory second edition (BDI-II). The data were analyzed in SPSS software version 20 using the Chi-square test, the independent t-test and the Mann-Whitney U test.Results: Of 215 participants, 84% were female. Their mean age was 34±10.5 years. The frequency of IBS was 13.5% among migraineurs. The most common type of IBS was undifferentiated (58.6%). IBS was more common among patients with migraine with aura (p=0.03). A significant association was observed between constipation dominant IBS and migraine (p=0.04). IBS patients were significantly depressed than non-IBS ones (p=0.01).Conclusion: IBS prevalence is high in migraine patients. Therefore, its diagnosis and treatment should be regarded in their management to improve their quality of life.

The IRRITABLE BOWEL SYNDROME (IBS) is a functional disorder of alimentary system, which may be caused by infectious gastroenteritis determined as post infectious IRRITABLE BOWEL SYNDROME (PI-IBS). The prevalence of PI-IBS is reported to be 4-36% in patients with infectious gastroenteritis. The exact mechanism leading to PI-IBS is not fully understood and some factors pertaining to infectious agent and host response may have a role. Rome IV diagnostic criteria provided new definition for PI-IBS. Though it is now considered a well-defined functional disorder of gastrointestinal system, no specific treatment is yet available for PI-IBS. This article reviews the latest issues on these heading about PI-IBS.

Background: Although the relationship between number of teeth and gastric disturbances has been recognized, limited data are available linking tooth loss and IRRITABLE BOWEL SYNDROME (IBS). This study aimed to investigate the relation between dental status and IBS among Iranian adults.Methods: In a cross-sectional study on 4669 Iranian adults, dental status was evaluated using a self-administered questionnaire. Participants were categorized into five main groups: those with full dentition (without denture), those with denture, individual who had lost 1-2 teeth, 3-5 teeth and half of one arch or more. IBS and its subtypes were defined using Rome III criteria.Results: After adjusting for different confounding variables, those who had lost 1-2 and 3-5 teeth had 1.35 and 1.33 times greater odds for IBS than fully dentate subjects, respectively. After controlling for different confounders, individuals who had denture had 103% greater chance to have constipation-predominant IBS than those with full dentition (Odds ratio: 2.03, 95% confidence interval: 1.29- 3.21). Neither in crude nor in adjusted models was any significant association between dental status and other subtypes of IBS. In addition, we did not find any association between losing half of one arch or more and IBS.Conclusion: We found that losing 1-2 or 3-5 teeth were significantly associated with increased risk of IBS. Having denture was related to constipation-predominant IBS. There should be further studies to confirm these findings.