Background: Fanconi anemia (FA) is a rare, autosomal recessive (AR) and multifactorial disorder. A high prevalence of FA observed in Iran is perhaps due to the high rate of consanguineous marriages. This study investigates the extent of short stature in patients with FA, the FREQUENCY of hypothyroidism in FA and the correlation between height and hypothyroidism.Methods: Eighteen patients with FA referred to the Pediatrics Clinic of Nemazee Hospital were selected based on specific congenital and malformational symptoms and bone marrow results. These patients were evaluated for weight, height, bone age, clinical goiter and thyroid function tests.Results: Eleven out of 18 patients (61%) had overt or compensated hypothyroidism. Short stature was found in 89% of patients with a mean height more than two standard deviation (SD) below the mean height for that age. There was no significant correlation between short stature and overt or compensated hypothyroidism. The mean height standard deviation score (SDS) of patients with normal thyroid function was also more than two SD deviation below the normal mean, revealing that short stature is an inherent feature of FA. In seven cases with goiter, only three had hypothyroidism. The mean±SD weight SDS was -1.03±0.99. The mean±SD bone age was 12±4.5 yr.Conclusion: According to the results of this study, our patients had a considerable prevalence of hypothyroidism and short stature was a common feature of FA. It is recommended that thyroid function test is necessary in these patients.

In this paper, the effect of a static synchronous compensator (STATCOM) influence on the FREQUENCY of islanded microgrids based on FREQUENCY control using fuzzy cooperative control is investigated. To achieve fast FREQUENCY control, instantaneous power balance between generation and consumption is inevitable, and it can be supplied through energy storage systems such as battery with a proper FREQUENCY control method. Besides, the FREQUENCY control of islanded microgrids could be studied under different circumstances, where one aspect analyzed is added to a flexible AC transmission system (FACTS) device, such as STATCOM, in the microgrids. Although STATCOM is charged with improving the voltage profile, it can affect FREQUENCY stability by adjusting the voltage very quickly. Due to the importance of refining FREQUENCY stability, two controller methods are compared: a classic PI controller and a fuzzy PID controller. Accordingly, the performance of STATCOM is evaluated via two scenarios. Based on simulation results, by applying the fuzzy PID controller to the microgrid, STATCOM can reach the nominal FREQUENCY. Moreover, with greater validation and investigation of this topic, this device could be an agreeable alternative to the battery energy storage system (BESS).

Consumption of alcohol contributes to disorders in brain. In this study, in order to detect the consumption of alcohol, electroencephalogram (EEG) signal of 20 participants (10 alcoholic and 10 control subjects) recorded by 64 channels was investigated. FREQUENCY and non-FREQUENCY features of EEG signal including power spectrum of signal, permutation entropy, approximate entropy, Katz fractal dimension and Petrosion fractal dimension were extracted to analyses the EEG signal. Statistical analysis was used to investigate the significant differences between the alcohol and control groups. The Davis-Bouldin (DB) criterion was used to select the best channel distinguishing between the alcoholic and non-alcoholic EEG signal. Results showed that between FREQUENCY features, power of lower2 alpha FREQUENCY decreased in alcoholic individuals and regarding the DB criterion, the CP3 channel (DB=1. 7638) showed the best discrimination between the alcohol and control groups. Also, among the non-FREQUENCY features, the Katz fractal dimension increased in the control group and FP2 channel (DB = 0. 862) had the best discrimination. Eventually, power of Lower2-alpha FREQUENCY band and Katz fractal dimension fed into the nearest neighbor classifier (KNN), 71% and 93% accuracy were achieved, respectively. According to the results, it can be concluded that the best feature and channel discriminating between alcohol and control groups is the Katz fractal dimension and FP2 channel.

In this paper, a distributed generation including diesel generators, wind turbines, and microturbines are introduced, and their mathematical model is described using the Taylor expansion method. With the goal of computational complexity eliminating, the reduced order model (ROM) of microgrid components is considered. The results of the studies indicate that the microgrid FREQUENCY is unstable. The main purpose of this paper is stabilizing the FREQUENCY of the microgrid by design modified linear controller. It is shown that the using proposed linear controller increases the dynamic response of the diesel generator and therefore can be constituted stable microgrid. The results show that the diesel generator can control the FREQUENCY of the microgrid in unwanted islanding and load change conditions. To verify the validity and feasibility of the proposed controller, several simulations results have been presented on MATLAB/Simulink software. The simulation results show the appropriate performance of the proposed controller for example in islanding mode, FREQUENCY restoration time is less than 1 (s) by using the proposed controller, as a result, the microgrid can be exploited in island mode.

Background and Aims: The BK virus a member of the Polyomaviruses family was first isolated from the urine of the kidney recipient. Infection with this virus and infection usually occurs in childhood [5-9 years] but most of the time [90%] of sera are positive and without symptoms. Polyomaviruses including the BK virus have also been suggested to be a contributing factor to some cancers in humans such as brain tumors, bone tumors, Kaposi’ s sarcoma, adrenal tumors, renal carcinoma, prostate cancer, urinary tumors, genital tumors etc. However, the topic still remains controversial. Materials and Methods: In this study, we report the presence of BK specific DNA sequences in bladder cancer by PCR and Nested PCR methods. Results: Our study results confirmed the presence of BK in 13. 7% of the samples by Nested PCR method. Conclusion: In conclusion, 51 samples 13. 7% of paraffin-embedded bladder cancer sample were confirmed by Nested PCR method.