A new section in MEJDD which is aimed to improve chinical decision making by presenting a real patient by an experienced clinician and who discuss the case and provide an evidence base decision making for diagnosis and treatment of patient in daily clinical practice.

Phosphorus (P) is one of the most vital elements for all living organisms which acts as a constituent of essential biomolecules such as nucleic acids, phospholipids, and phosphosugars, and as a major contributor to almost all metabolic reactions including photosynthesis, respiration, and energy delivery. It is one of the most needed nutrients for plant growth and development. Despite high levels of P in the soil, plants absorb it only in the soluble inorganic form of free phosphate ion (Pi) which is scarce in soil. Therefore, there has been a large demand for Pi fertilizers to secure crop yields, yet its deposition in soil and gradual run-off into water reservoirs lead to chains of events that cause irreversible damages to ecosystems. Researches, including genome-wide data analyses, have revealed interesting molecular aspects of plant adaptive strategies to deal with low Pi concentrations in soil. These include the higher expression of acid phosphatases and Pi transporters as well as the secretion of organic acids in the rhizosphere that maintain cellular Pi homeostasis in order to keep metabolic reactions running. Describing the cycle of Pi exchange between physical and biological worlds, the extent to which current agricultural practices are disturbing the cycle, the necessity of introducing lessdestructive methods of providing Pi, and alternative measures and solutions for sustainable agriculture will be discussed in this review.

Every year, some 3. 9 million girls aged 15 to 19 years undergo unsafe abortions (1). Approximately 16 million girls aged 15 to 19 years and 2. 5 million girls under 16 years give birth each year in developing regions (2, 3). Complications during pregnancy and childbirth are the leading cause of death for 15 to 19 year-old girls globally (4). Adolescent mothers (ages 10 to 19 years) face higher risks of eclampsia, puerperal endometritis, and systemic infections than women aged 20 to 24 years (5, 6). The term "adolescent" is often used synonymously with "teenager". In this sense "adolescent pregnancy" means pregnancy in a woman aged 10– 19 years (2, 7). Pregnant teenagers face many of the same pregnancy related issues as other women. There are additional concerns for those under the age of 15 as they are less likely to be physically developed to sustain a healthy pregnancy or to give birth (8). For girls aged 15– 19, risks are associated more with socioeconomic factors than with the biological effects of age (9). Risks of low birth weight, premature labor, anemia, and pre-eclampsia are connected to biological age, being observed in teen births even after controlling for other risk factors (such as accessing prenatal care etc. ) (5, 6).

Paragangliomas are neoplasms of neural crest origin. In the head and neck, they uncommonly involve the larynx. The distinction between paragangliomas and other neuroendocrine tumors can be difficult. Precise diagnosis is important in order to optimize patient treatment. Diagnosis relies mostly on histopathologic examination followed by immunohistochemistry. Here we report a 77-year-old woman with laryngeal paraganglioma that initially misdiagnosed as laryngeal carcinoid tumor.