The radiography showed localized soft tissue calcification of which the possible diagnoses were: soft tissue tumor with calcified features, a metastatic calcification in the setting of abnormal CALCIUM or phosphorus metabolism,¹ and an old infection such as a calcified granuloma. In this case there was history of injection of intramuscular CALCIUM compound. The main diagnostic clues were in her history of intramuscular injection and radiographic finding of the hip. No specific major illness was found upon clinical evaluation. She had three intramuscular injections (30 mL total volume), of CALCIUM GLUCONATE (10% solution) weekly for three times in her left buttock….

Four hundred and eighty mixed-sex broiler chicks aged 3 hrs after hatching were allotted according to a completely random design in a 6 × 2 × 2 factorial schedule into 2 groups of 12 replications of 20 chicks each. The main experimental factors were fasting for 0, 6, 12, 24, 36, and 48 hrs after chick placement, CALCIUM GLUCONATE (Ca-glu) injection (0 and 0.6 mL) and sex (male and female). Independent of sex, live body weight (BW) of chicks decreased linearly (Y=43.36-0.109BW0h, r2=0.876) as neonatal fasting extended. Injection of 0.6 mL Ca-glu at 3 hrs post hatching did not affect weight loss of chicks. Yolk residuals (YR) utilized linearly (Y=5.75-0.062YR, r2=0.956) by 0.062 g/hr in neonate fasted chicks showing no effect for Ca-glu injection. Neonatal fasting periods longer than 12 hrs increased liver weight (P<0.05). The mean absolute and proportional (% of BW0h) breast and leg weight were reduced linearly as neonatal fasting extended (P<0.05). Serum glucose concentration in both sexes increased up to 6 hrs fasting, then reduced linearly to 150 mg/dL after 48 hrs feed withdrawal. The Caglu treatment influenced serum glucose level for a short period up to 6 hrs of fasting. Serum Ca concentration sharply increased up to threefold in the birds received Ca-glu injection resulting in acute hypercalcemia, then decreased to the initial level after 24 hrs feed withdrawal. The mean serum level for creatinine, uric acid, cholesterol, HDL, albumins and total proteins significantly increased during the fasting periods of 6 to 48 hrs and significantly elevated in the birds received 0.6 mL Ca-glu injection compared with the non treated chicks. It was concluded that subcutaneous administration of 0.6 mL Ca-glu in the chick's neck did not suitably support the increased metabolic demands for glucose and CALCIUM in feed deprived neonate chicks.

Background: Administration of Protamine sulfate for heparin neutralization after cardiopulmonary bypass may be associated with adverse reactions such as transient hypotension to cardiovascular collapse. Although catastrophic events are rare and occur only in 2.6% of cardiac surgeries, it is associated with adverse postoperative outcome. The aim of this study is to investigate whether bolus administration of CALCIUM GLUCONATE can minimize the adverse hemodynamic effects of protamine.Patients and Methods: This randomized clinical trial (RCT) prospective study was conducted between Feb. 2006 to Dec. 2008. The patients were randomly allocated into three groups including group A (42 patients) who received only protamine after weaning from cardiopulmonary, group B (44 patients) concomitantly treated with protamine sulfate and CALCIUM GLUCONATE, and group C (40 patients) receiving CALCIUM GLUCONATE 5 minutes before administration of protamine. Hemodynamic variables such as systolic and diastolic blood pressures, mean of arterial pressure, central venous pressure and heart rate were obtained 0, 2, 4, 6, 8 and 10 minutes after protamine administration from each group.Results: Systolic blood pressure in groups A (control) and C (CALCIUM administration before protamine) 0,2,4,6,8 and 10 minutes after protamine administration initially decreased and increased subsequently (P=0.228). Also no statistically significant difference was found in diastolic blood pressure (DBP), mean arterial pressure (MAP), central venous pressure (CVP), and heart rate (HR) in 0,2,4,6,8, and 10 minutes in any of the three groups. Conclusion: In our study, hemodynamic changes in 10 minutes after protamine administration for heparin neutralization in patients with good left ventricular systolic function after coronary artery bypass grafting surgery were mild, and prophylactic CALCIUM GLUCONATE administration concurrent with or before protamine injection was not recommended.

Statement of the Problem: A major objective of investigators is to clarify the role of metabolites in achievement of maximum tooth movement with minimal root damage during orthodontic tooth movement (OTM).Purpose: The aim of this study was to determine the effect of administration of thyroid hormone, prostaglandin E2, and CALCIUM on orthodontic tooth movement and root resorption in rats.Materials and Method: Sixty four male Wistar rats were randomly divided into 8 groups of eight rats each: 1- 20mg/kg thyroxine was injected in traperitoneally after installation of the orthodontic appliance. 2- 0.1 ml of 1 mg/ml prostaglandin E2 was injected submucosally. 3- 10% (200 mg/kg) CALCIUM GLUCONATE was injected. 4- Prostaglandin E2 was injected submucosally and 10% CALCIUM was injected intraperitoneally. 5- Thyroxine was injected intraperitoneally and prostaglandin E2 was injected submucosally. 6- 20mg/kg thyroxine with CALCIUM was injected. 7- Prostaglandin E2 was injected submucosally with CALCIUM and thyroxine. 8- Distilled water was used in control group. The orthodontic appliances comprised of a NiTi closed coil were posteriorly connected to the right first molar and anteriorly to the upper right incisor. OTM was measured with a feeler gauge. The mid-mesial root of the first molar and the adjacent tissues were histologically evaluated. The Data were analyzed by one-way ANOVA and Student-Newman-Keuls test.Results: The highest mean OTM was observed in the thyroxine and prostaglandin E2 group (Mean±SD = 0.7375±0.1359 mm) that was significantly different (p< 0.05). A significant difference (p< 0.05) in root resorption was observed between the prostaglandin E2 (0.0192±0.0198 mm2) and the other groups.Conclusion: It seems that the combination of thyroxine and prostaglandin E2, with a synergistic effect, would decrease the root resorption and increase the rate of orthodontic tooth movement in rats.

Introduction: The most common cause of knee pain is knee osteoarthritis, many surgical and non-surgical treatments have been proposed but the preferred treatment remains unknown. One of the non-surgical treatments was PRP (plasma reach platate) injection in these patients. Various studies have shown the improvement of the effect of PRP injection with substances such as CALCIUM GLUCONATE, so the aim of this study was to evaluate the effectof PRP with and without CALCIUM GLUCONATE on the clinical results of intra-articular injection of this substance in patients with knee osteoarthritis. Methods: This was a cohort study in which patients were divided into two groups: PRP injection and PRP injection with CALCIUM GLUCONATE. The results of the study were evaluated by KOOS questionnaire and pain by VAS. A significance level of 0. 05 was considered. Result: Generally, during the study, the pain level in patients after receiving both treatments significantly decreased during the six-month period, while the pain in the case group significantly decreased. (P Value <0. 05). Discussion: From the results of this study, it can be concluded that simultaneous injection of PRP and CALCIUM GLUCONATE can further improve the results of injection.