Rudbar Lorestan dam is constructed on Abrudbar River, 100 km south of Aligudarz city. There is a segment of Main Recent Fault (MRF) called Saravand-Baznavid Fault (SBF) at 1.6 km south of dam SITE. Using Automatic Extraction Method, based on STA Algorithm, lineaments were extracted from sattelite images and Shaded Relif Model. For detailed structural analysis, the study area was divided into three zones based on geological map. In Eslamabad Fault zone, Eslamabad fault is the main structural element, that is likely of P-type fractures. The main structure in the SBF zone is Saravand-Baznavid ACTIVE Fault, which caused the drainage to be displaced as much as 500-1000m in the northern height of study area. In the Dam axis zone, the main structure is F1 fault. This fault is about 150 meters in length with right lateral strike slip component. Thermoluminescence dating, sence of movement, dominant slikenside, and the orientation of groove marks on the fault plane indicate this fault to be ACTIVE. Large dicplacements along with strike-slip faults in the study area, such as F1 fault, have been considered using shear zone and enechelon models. However, the main faults in the study area is SBF, that is relate in an enechelon PATTERN to seismic Dourud fault and has the right potential to movement in the future.

The goal of the present research is Student self-efficacy modeling based on mothers' early maladaptive schemas and self-concept and irrational beliefs of the students. All students of last grade of primary schools who attended classes during the academic year 1394-95 in the city of Tehran, was the statistical population of this study. For the selection of sample population, the muti-stage sampling methodology has been applied and a total of 317 students of both genders have been selected for study. Each student responded to three questionnaires and their mothers answered to a questionnaire that was sent to them by students. Data were analyzed by using multiple regression and path analysis. Results showed that among the fifteen components of early maladaptive schemas of mothers, five schemas directly and indirectly reduce students' academic self-efficacy, and the role of mediation of self-concept and irrational beliefs of the students were confirmed. In addition, the results showed that self-concept and irrational beliefs are inversely related to one another.

Heterogeneous Ziegler-Natta and homogeneous metallocene catalysts exhibit greatly different ACTIVE SITE nature in olefin polymerization. In our previous study [1], it was reported that MgCl2-supported titanocene catalysts can generate both Ziegler-Natta-type and metallocene-type ACTIVE SITEs according to the type of activators. The dual ACTIVE SITE nature of the supported titanocene catalysts was further explored in the present study: The influence of the ligand structure of titanocene precursors was studied on the nature of ACTIVE SITEs when supported on MgCl2 in ethylene and propylene homopolymerization, and ethylene/1-hexene copolymerization. It was found that the reducibility of titanocene precursors by alkylaluminum is closely related to the appearance of the dual ACTIVE SITE nature, while the kind of olefin did not affect the type of ACTIVE SITEs formed during polymerization. The Ziegler-Natta-type ACTIVE SITEs produced poorly isotactic polypropylene and less branched polyethylene, while the metallocene-type ACTIVE SITEs produced atactic polypropylene and exhibited much higher incorporation efficiency for 1-hexene.

Objective(s): Vinblastine is antimitotic, anticancer medicine that disturbs normal microtubule formation and favours depolymerisation. Structural study and finding the ACTIVE SITE of vinblastine are the targets of this research.Materials and Methods: Vinblastine was optimized in vacuum and then in different solvents by Density Functional Theory (DFT) method. Nuclear Magnetic Resonance (NMR) shift measurements were made in different solvents by various dielectric constants by Continuous Set of Gauge Transformations (CSGT).Results: The best structure and function of vinblastine was established. The conformational preferences may be attributed to stereoelectronic effects. The results showed that the structure of vinblastine is more stabile in water rather than the other media. The most ACTIVE atoms of vinblastine were realized by various spectra of vinblastine in different media including vacuum and diverse solvents.Conclusion: Discovery of ACTIVE SITE of vinblastine that could bind to tubulin to perform the antimitosis and anticancer effect in process of cell division was accomplished in this investigation. These data can be applicable to study the binding SITE of vinblastine-tubulin complex.

Chitinases are one of the important industrial enzymes which have significant role in different industries such as digestion of chitin and chit oligosaccharides, bioremediation and control of plants pathogenic fungal as well as insects. This enzyme catalyzes theb1®6 glycoside bond and then hydrolyses chitin polymers. chitinases consists of a (b/a) 8-barrel catalytic domain contain of conserved sequence called DXDXE motif on b4 strand which D, E and residue around of this conserved sequence have essential role in cleavage and hydrolysis of the glycosidic bond. Study of ACTIVE SITE adjacent amino acids can help us to understand their function in catalytic properties. In this project are mutated Ser390 and Gly191 for investigating role of this two residue existing in the adjacent of conserved sequence at catalytically process of Serratia marcescens B4A chitinase and after of cloning in expression vector and analysis of expression with SDSPAGE are investigated effect of two mutations on the enzyme activity

Nowadays, environmental hazards that originated from inappropriate management of waste are one of the main problems of the country. Therefore, the development of waste management system and new and advanced technologies entry is necessary. Waste disposal by incinerator is an effective method. Unlike landfill, the use of incineration does not require long-term care and there is the possibility of energy extraction. One of the main disadvantages of this method is emission of air pollutants from the stuck of incinerators and management of the residual wastes such as ash. Therefore, selecting the best place for construction of the municipal waste incineration power plant will increase its benefits, reduce costs and eliminate community dissatisfaction by identifying and considering the involved and effective factors such as environmental, economic and social factors. In this paper, literature reviewes, searching for valid universal guidelines and the related articles in databases were used to introduce and compare the criteria mentioned for locating the municipal waste incineration power plant as one of the most important steps in designing a comprehensive waste management system.

Monoamine oxidase-B (MAO-B) is a mitochondrial outer membrane flavoenzyme that is a well-known target for anti-depressant and neuroprotective drugs. MAO-B is one of two flavin-dependent isozymes (the other being MAO-A) that function in the oxidative determination of neurotransmitters and exogenous arylalkylamines. Mammalian MAOs are bound to the outer mitochondrial membrane through a C-terminal transmembrane poly peptide. These oxidases have long been a pharmacological focus because both reversible and irreversible inhibitors of MAO-A and B have been used clinically in the treatment of neurological disorders. The ACTIVE SITE of MAO-B consists of a 420  Å3- hydrophobic substrate cavity interconnected to an entrance cavity of 290 Å3. Advances in computer hardware, in force fields, and in molecular dynamics simulation methods and software have enabled increasingly more sophisticated studies of protein and drug structures and dynamics. On the basis of the experimental information about the substrate and inhibitor binding SITE of human MAO-B atomistic molecular dynamics simulation was performed to determine what factors govern inhibitor specificity and the inhibitor binding process, the ACTIVE SITE loop, and several key residues within the binding pocket.The simulations demonstrate that the average energy of interaction between inhibitor and MAO-B residues provide researchers with valuable tools for designing effective MAO-B inhibitors as well as outline a method that can be translated to the study of other enzymeinhibitor complexes.

In this study, the structural and electronic properties of a boron nitride nanocone (BNNC) with 120° disclination were investigated using density functional theory calculations. In the considered model, there are one tetragonal ring and 56 hexagonal rings, with the mouth of nanocone saturated by the hydrogen atoms. In the second step, with making defect in boron nitride nanocone and transverse cutting on its apex, the structure similar to porphyrin was induced in preliminary boron nitride nanocone and the P-BNNC compound was produced. In the third step, the Mg2+ ion was placed in the center of the produced core in P-BNNC and the chlorophyll like structure (Mg- P-BNNC) was formed. In the final step, the interactions between CO2, CO, H2 and O2 gas molecules and the exterior and interior surface of Mg- P-BNNC compound was studied. The CO2 and H2 gas molecules adsorbed only on the Mg metal atom on the exterior SITE but, the CO molecule was adsorbed from both the exterior and interior SITE of Mg- P-BNNC. However, the O2 gas molecule has high adsorption only from the interior SITE of Mg- P-BNNC. With the adsorption of CO2, CO and H2 gases on Mg- P-BNNC, the band gap is approximately constant and so, the conductivity of Mg- P-BNNC molecule has not significantly changed. The noticeable point is that the amount of Mg- P-BNNC band gap, as well as conductivity, has significant change with the adsorption of O2 gas on its interior SITE. So, the Mg- P-BNNC is the good and selective sensor for the O2 gas in the presence of CO2, CO and H2 gases. The Density of State (DOS) and Natural Bond Orbital (NBO) calculations have confirmed the above results.