Introduction: urtica dioica is a herbal medicine used for the treatment of diabetes. This study aimed to investigate the effects of urtica dioica on cardiovascular function and fasting blood sugar in patients with type II diabetes.Materials and Methodgy: In this quasi-experimental study, 20 males with type II diabetes who met the inclusion criteria were selected and randomly divided into two groups (n=10) of urtica dioica and control. In pre- and post-test, fasting blood sugar, blood pressure, resting heart rate, and maximal oxygen consumption were measured. To analyze the measured indices, t-test was run (P≤0.05) Results: A significant decrease were observed in body weight, fasting blood sugar, diastolic blood pressure, and resting heart rate, while a significant increase was noted in maximal oxygen consumption in urtica dioica group (P<0.05). In addition, significant differences were observed in fasting blood sugar, diastolic blood pressure, resting heart rate, and maximal oxygen consumption between the urtica dioica and control groups (P<0.05).Conclusion: According to the findings of the present study, use of urtica dioica herbal tea is an effective way to control blood glucose and improve cardiovascular function in patients with type II diabetes.