Cheezeh copper oxide deposit is located in 90 Km from Ghazvin, North West of Iran. A pre-feasibility study was carried out to select process route for the deposit. According to the mineralogical studies, malachite is the main mineral of copper containing about 3% Cu. Vat and agitation processes were chosen as leaching method. Using Taguchi method for experimental design, effects of acid concentration, particle size, and time on copper leaching were studied.By obtaining the optimum amounts of experimental parameters, the four alternatives for leaching of the copper oxide suggested.Considering the four alternatives for leaching and two alternatives for copper recovery from PLS, in total eight alternatives were verified from economical point of view. After estimating capital and operating costs, economical estimations were made by “process ranking method”. Agitation leaching in 3.75 hours on the particle size of finer than 350 µ in an acid concentration of 185 gr/lit with a recovery of 94-95% was the best alternative.