Objectives: To determine the morbidity and graft survival rate in kidney recipients aged between 6 and 18 years who had undergone kidney transplantation in Imam Reza Hospital, Mashhad, northeastern Iran during 1992-2009.Methods: Of 1585 kidney recipients who had undergone kidney transplantation in our center during 1992- 2009, 168 patients aged from 6–18. Neurogenic bladder, reflux nephropathy, posterior urethral valve, prunebelly syndrome and chronic glomerulonephritis were diagnosed to be the cause of renal failure in these patients.22% of the donors were related living, 66% were unrelated living and 12% were cadaveric. Immunosuppressive therapy was initiated with cyclosporine, mycophenolate mofetile, azathiporine and prednisolone. Kaplan-Meier survival analysis was used to assess graft and patient survival while log-Rank test was used to assess the effect of kidney source and the time of renal transplant.Results: All the studied patients developed immediate diuresis. Surgical complications included 2 urinary fistulas, 2 ureteral strictures and 3 clinical lymphoceles all of which were surgically managed. Chronic rejection and recurrence of the underlying renal disease were the most common cause of graft loss. Graft survival rate after 1, 2, 5, and 10 years of kidney transplantation were 97%, 88%, 79%, 65% and 53%, respectively.Conclusion: kidney transplantation in children results in physical growth improvement and mental development. Graft survival rate due to chronic rejection, underlying kidney disease recurrence and incompliance in taking medicines remain to be a problem.