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23363

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اعمال فیلتر

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2337

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فیلترها/جستجو در نتایج    

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متن کامل


مرکز اطلاعات علمی SID1
مرکز اطلاعات علمی SID
اسکوپوس
مرکز اطلاعات علمی SID
ریسرچگیت
strs
نویسندگان: 

اطلاعات دوره: 
  • سال: 

    2019
  • دوره: 

    76
  • شماره: 

    11
  • صفحات: 

    0-0
تعامل: 
  • استنادات: 

    71
  • بازدید: 

    75
  • دانلود: 

    3411
کلیدواژه: 
چکیده: 

آمار یکساله:  

بازدید 75

دانلود 3411 استناد 71 مرجع 0
اطلاعات دوره: 
  • سال: 

    2020
  • دوره: 

    7
  • شماره: 

    3
  • صفحات: 

    35-46
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    16304
  • دانلود: 

    12986
چکیده: 

Background and objectives: Positive role of saffron in human health promotion has been investigated in widespread researches. anticancer property, neuroprotection, protection of cardiovascular system and several positive properties are reported for saffron customers. The aim of this study was assessment of saffron weakness against light damage in rat retina. Methods: Gene profiles of control samples (C group) and light damage (L) groups were extracted from Gene Expression Omnibus (GEO) and compared with similar samples in the presence of saffron. The unprotected differentially expressed genes (DEGs) were evaluated via network analysis and pathway investigation. The critical genes which were not protected by saffron were identified and discussed. Results: Numbers of 67 DEGs were investigated via protein-protein interaction (PPI) network analysis, pathway assessment, and action map investigation. Findings indicated that STAT1, JUN, FOS, and STAT3 were the crucial genes that were not protected by saffron against light damage in rat retina. Conclusion: It may be necessary that consumption of saffron require a suitable protocol to avoid from possible disadvantages; however, saffron is well known for its benefits in human nutrition.

آمار یکساله:  

بازدید 16304

دانلود 12986 استناد 0 مرجع 3465
اطلاعات دوره: 
  • سال: 

    2000
  • دوره: 

    44
  • شماره: 

    1
  • صفحات: 

    101-104
تعامل: 
  • استنادات: 

    315
  • بازدید: 

    3585
  • دانلود: 

    9195
کلیدواژه: 
چکیده: 

آمار یکساله:  

بازدید 3585

دانلود 9195 استناد 315 مرجع 0
گارگاه ها آموزشی
نویسندگان: 

AHAMED K.N. | KUMAR V. | RAJA S. | MUKHERJEE K. | MUKHERJEE P.K.

اطلاعات دوره: 
  • سال: 

    2005
  • دوره: 

    4
  • شماره: 

    2
  • صفحات: 

    105-109
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    32740
  • دانلود: 

    12456
چکیده: 

The effect of alcoholic extracts of leaf from Araucaria bidwillii Hook. [ABH] (Family: Araucariaceae) was evaluated in experimental models of pain and inflammation. Oral administration of 100, 200 and 300 mg/kg of leaf extracts of ABH were used for the above study. The leaf extract at 300 and 200 mg/kg showed significant reduction in acetic acid induced writhings in mice with a maximum effect of 65.1% reduction at 300 mg/kg dose. In hot plate method the percentage of pain inhibition was found to be 81.69% and 66.1% with both the tested dose of the leaf extract respectively. The effect produced by the alcoholic extract at the highest dose was comparable to that of acetyl salicylic acid at 100 mg/kg (91.52%). The alcoholic extracts of A. bidwillii showed significant inhibition in carrageenan (18.61%, 32.12% and 45.64%) and serotonin (32.81%, 38.68% and 40.75%) induced hind paw oedema in rats at 100, 200 and 300 mg/kg of the ABH extract respectively. The anti-inflammatory effects showed by the extract were comparable to that of standard indomethacin 5 mg/kg (68.51% and 63.28%). The results suggest that the anti-inflammatory and analgesic effect of the extracts as claimed in folklore medicine, which may be mediated via both peripheral and central mechanisms. 

آمار یکساله:  

بازدید 32740

دانلود 12456 استناد 0 مرجع 3552
نویسندگان: 

VERDRENGH M. | JONSSON I.M. | HOLMDAHL M. | TARKOWSKI A.

نشریه: 

INFLAMMATION RESEARCH

اطلاعات دوره: 
  • سال: 

    2003
  • دوره: 

    52
  • شماره: 

    8
  • صفحات: 

    341-346
تعامل: 
  • استنادات: 

    315
  • بازدید: 

    6211
  • دانلود: 

    9195
کلیدواژه: 
چکیده: 

آمار یکساله:  

بازدید 6211

دانلود 9195 استناد 315 مرجع 0
نویسندگان: 

Bagheri Hosseinabadi Zahra | Abbasifard Mitra

اطلاعات دوره: 
  • سال: 

    2020
  • دوره: 

    3
  • شماره: 

    4
  • صفحات: 

    50-62
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    8194
  • دانلود: 

    4812
چکیده: 

Polyphenols are micronutrients with an extensive range of biological characteristics including a reduction in inflammation features. Pistachio is rich in polyphenols, and therefore, contains the anti-inflammatory potential for various anti-inflammatory conditions. To date, beneficial anti-inflammatory effects of pistachio or its derivatives have been demonstrated in several inflammatory conditions such as colitis and paw edema. A number of conditions, including diabetes, obesity, and cardiovascular disorders have also been found to benefit from pistachio supplementation. Growing evidence suggests that pistachio could be more widely used in inflammatory conditions. Pistachio and its derivatives seem to exert anti-inflammatory effects through several direct and indirect mechanisms. However anti-inflammatory properties of pistachio need to be further investigated in the context of other inflammatory conditions such as inflammatory and autoimmune arthritis, systemic lupus erythematous, tendonitis etc.

آمار یکساله:  

بازدید 8194

دانلود 4812 استناد 0 مرجع 0
strs
نویسندگان: 

NOZAKI Y. | YAMAGATA T. | SUGIYAMA M.

نشریه: 

CLINICAL IMMUNOLOGY

اطلاعات دوره: 
  • سال: 

    2006
  • دوره: 

    119
  • شماره: 

    3
  • صفحات: 

    272-279
تعامل: 
  • استنادات: 

    315
  • بازدید: 

    7613
  • دانلود: 

    9195
کلیدواژه: 
چکیده: 

آمار یکساله:  

بازدید 7613

دانلود 9195 استناد 315 مرجع 0
اطلاعات دوره: 
  • سال: 

    2007
  • دوره: 

    0
  • شماره: 

    18
تعامل: 
  • بازدید: 

    2835
  • دانلود: 

    0
کلیدواژه: 
چکیده: 

Introduction: Inflammation is a complex process that related to inflammatory disease such as myocard infarction, rheumatoid arthritis, parkinson and multiple sclerosis. Inducible nitric oxide synthase (iNOS), cyclooxygenase II (COX-II) and release of their products (nitric oxide (NO) and prostaglandin E2 (PGE2)) by inflammatory macrophages have critical role in inflammatory conditions. anti-inflammatory drugs have unpleasant side effect and sometimes are not effective. So, scientists try to find more effective compound. Rose Bengal (RB) is water soluble xanthine dye that has been used in medicine as a safe compound. In this study, anti-inflammatory effect of Rose bangal was investigated in inflammatory macrophages in vitro.Methods: J774A.1 macrophages (125×103 cell/well in 96-well plate) were treated with bacterial lipopolysachharide (stimulator for iNOS and COX-II and production of pro-inflammatory cytokines) and different concentration of Rose Bengal (10-200 micromolar) and incubated in 37oc. After 18 hours, NO production (by Griess method) and PGE2, TNF-α and IL-1 (By ELISA) were measured. Wester blotting method was used for quantitative measurement of iNOS and COX-II expression.Results: Rose Bengal caused a significant decrease (p<0.001) in the production of NO, PGE2 and pro-inflammatory cytokines in a dose-dependent manner. This decrease was associated with the decrease in iNOS and COX-II expression. So, these results showed significant anti-inflammatory effect of Rose bangal and the mechanism of its action.Conclusion: Rose Bengal could be considered as a promising anti-inflammatory agent for the treatment of inflammatory diseases in future.

آمار یکساله:  

بازدید 2835

دانلود 0
اطلاعات دوره: 
  • سال: 

    2019
  • دوره: 

    8
  • شماره: 

    1
  • صفحات: 

    54-61
تعامل: 
  • استنادات: 

    0
  • بازدید: 

    12521
  • دانلود: 

    8868
چکیده: 

Metformin is one of the oldest and commonly used blood sugar lowering drugs, having limited side effects and used as the first line treatment in patients suffering from diabetes mellitus. Moreover, various studies have emphasized on the anti-inflammatory and antioxidant role of metformin, with multiple mechanisms, which activation of AMPK by metformin has had a key role in many of them. During the searches on the internet websites of PubMed, Elsevier, Google Scholar, and Science Direct, 76 papers related to the anti-inflammatory and antioxidant role of metformin were selected and reviewed since 2003 to 2017. At the cellular level, metformin suppresses the inflammation in many cases and reduces or eliminates inflammatory factors mainly through dependent mechanisms and sometimes independent of AMPK at the cellular level and through other ways at the systematic levels. It is also effective in reducing the level of oxidative stress factors by regulating the antioxidant system of the cell. All evidence suggests the antioxidant and anti-inflammatory role of metformin in various conditions. Metformin can be an appropriate treatment option for many diseases, which inflammatory processes and oxidative stress play a role in their pathogenesis.

آمار یکساله:  

بازدید 12521

دانلود 8868 استناد 0 مرجع 0
همایش: 

GRADUATE CONFERENCE

اطلاعات دوره: 
  • سال: 

    2016
  • دوره: 

    0
  • شماره: 

    6
تعامل: 
  • بازدید: 

    1050
  • دانلود: 

    0
چکیده: 

INTRODUCTION: THERE ARE EVIDENCE REGARDING anti-inflammatory AND antiCANCER EFFECT OF EXERCISE. HOWEVER, THE AIRWAY RESPONSE TO EXERCISE IN ATHLETES POPULATION HAS BEEN POORLY INVESTIGATED ESPECIALLY IN WOMEN. IN THE PRESENT STUDY PULMONARY FUNCTION TEST CHANGES IN PHYSICALLY FIT FEMALE STUDENTS WAS EXAMINED...

آمار یکساله:  

بازدید 1050

دانلود 0
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