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Information Seminar Paper

Title

BIOCHEMICAL CHARACTERIZATION OF DENILEUKIN DIFTITOX IMMUNOTOXIN: THE STUDY ON CHEMICAL INSTABILITY USING WESTERN BLOT AND RP-HPLC

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Abstract

 BACKGROUND AND AIM: DENILEUKIN DIFTITOX IS A TYPE OF IMMUNOTOXIN AND FUSION TOXIN FOR CANCER TREATMENT WITH LEUKEMIA, LYMPHOMA AND MELANOMA. RECOMBINANT DENILEUKIN DIFTITOX IS MADE BY COMBINING A PART OF THE AMINO ACID SEQUENCES FOR IL-2 FOLLOWED BY THE SEQUENCES FOR DIPHTHERIA TOXIN. THE IL-2 PART OF THE DRUG ATTACHES TO THE CANCER CELLS AND THEN THE TOXIN KILLS THE TUMOR CELLS. ...

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