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Title

HPTLC DETERMINATION OF PERPHENAZINE IN HUMAN URINE SAMPLE AFTER PRECONCENTRATION USING DISPERSIVE PERPHENAZINE MAGNETIC MOLECULAR IMPRINTED POLYMER: COMPARING WITH HPLC RESULTS

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Abstract

 THERAPEUTIC DRUG MONITORING (TDM) PLAYS AN INCREASINGLY IMPORTANT ROLE IN THE CLINICAL USE OF TRICYCLIC ANTIDEPRESSANTS SUCH AS PERPHENAZINE (PPZ) AND OTHER PSYCHIATRIC DRUGS [1]. TO THE BEST OF OUR KNOWLEDGE, TECHNIQUES AVAILABLE FOR MONITORING PERPHENAZINE AND OTHER NEUROLEPTICS ARE GAS CHROMATOGRAPHY (GC) AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY (HPLC). ...

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