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Title

ORGANOCATALYTIC, RAPID AND FACILE SYNTHESIS OF SPIROOXINDOLE DERIVATIVES IN THE PRESENCE OF POTASSIUM PHTHALIMIDE-N-OXYL (POPINO) USING BALL MILLING TECHNIQUE

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Abstract

 THE SPIROOXINDOLE SYSTEM IS THE CORE STRUCTURE OF MANY PHARMACOLOGICAL AGENTS AND NATURAL ALKALOIDS.1, 2 AMONG THESE HETEROCYCLES, 1, 4-DIHYDROPYRIDINES FORM A CLASS WITH BIOLOGICAL ACTIVITY.3 ALTHOUGH SEVERAL METHODS FOR THE SYNTHESIS OF SPIROOXINDOLES HAVE BEEN REPORTED, THERE IS STILL A...

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