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Title

SYNTHESIS AND EVALUATION OF ANTIBACTERIAL EFFECT OF SILVER NANOPARTICLES, IN COMBINATION WITH CIPROFLOXACIN

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 Start Page | End Page

Abstract

 BACKGROUND AND AIM: ANTIMICROBIAL RESISTANCE IS PRESENT IN ALL PARTS OF THE WORLD AND GRADUAL DEVELOPMENT OF ANTIBIOTIC RESISTANT BACTERIA IS PRODUCING SEVERE GLOBAL THREAT. SILVER NANOPARTICLES (AGNPS) HAVE BEEN SHOWN GREAT INTEREST BECAUSE OF THEIR POTENTIAL ANTIBACTERIAL EFFECTS. THIS STUDY WAS AIMED AT SYNTHESIZING AGNPS AND EVALUATION OF THEIR ANTIMICROBIAL EFFECTS IN COMBINATION WITH CIPROFLOXACIN.METHODS: THE NANOPARTICLES USED IN THIS STUDY WERE PREPARED FROM AGNO3 USI NG NABH4 AS A REDUCING AGENT. THESE AGNPS WERE CHARACTERIZED THROUGH UV -VIS SPECTROSCOPY AND SCANNING ELECTRON MICROSCOPY (SEM). FINALLY, MINIMAL INHIBITORY CONCENTRATION (MIC) OF THESE AGNPS IN COMBINATION WITH CIPROFLOXACIN AGAINST PATHOGENIC ESCHERICHIA OLI WAS DETERMINED IN MUELLER HINTON BROTH….

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