Seminar Paper

Paper Information

video

sound

Persian Version

View:

726

Download:

Cites:

Information Seminar Paper

Title

STUDY OF ANTAGONISTIC EFFECTS OF ANTIBIOTICS AND PHENOTYPIC EXTENDED- SPECTRUM Β - LACTAMASESPRODUCEDINPSEUDOMONAS AERUGINOSA AND ACINETOBACTER BAUMANNII ISOLATES

Pages

 Start Page | End Page

Abstract

 BACKGROUND AND AIM: PSEUDOMONAS AERUGINOSA AND ACINETOBACTER BAUMANNII CAN SURVIVE IN HOSPITAL CONDITIONS AND CAUSE DIFFERENT DISEASES INCLUDING HOSPITAL INFECTIONS. SO, A PERIODIC ASSAY OF DRUG RESISTANCE PATTERN AND IN COMBINED THERAPY, ANTAGONISTIC EFFECTS OF THESE DRUGS, SHOULD BE DONE IN HOSPITAL ACQUIRED ISOLATES.METHODS: IN THIS STUDY, NON-FERMENTATIVE BACILLI WERE COLLECTED FROM ALINASAB AND SHOHADA HOSPITALS IN TABRIZ AND IMAM KHOMEINI HOSPITAL IN UREMIA. THEY WERE IDENTIFIED USING COMMON LABORATORY METHODS. ANTAGONISTIC EFFECTS OF DRUGS CONSUMED WERE ASSAYED BY DISC DIFFUSION AGAR METHOD, AND PHENOTYPIC DETECTION OF EXTENDED- SPECTRUM Β -LACTAMASE ENZYME (ESBLS) BY USING DISK DIFFUSION AGAR METHOD AND COMBINED DISK METHOD.RESULTS: IN THIS STUDY, FREQUENCY OF RESISTANCE IN 60 PSEUDOMONAS AERUGINOSA AND 13 ACINETOBACTER BAUMANNII ISOLATES WAS OBSERVED IN %75AND 92.3% AGAINST TO CARBENICILLIN, %60 AND 92.3% AGAINST TO CEFTRIAXONE, %50 AND 92.3% TO CEFTAZIDIME, %33.3 AND 76.9% TO IMIPENEM, RESPECTIVELY. MEANWHILE, NONE OF THE ISOLATES SHOWED RESISTANCE AGAINST COLISTIN. THE INCIDENCE OF ESBLS IN PSEUDOMONAS AERUGINOSA ISOLATES, USING DISK DIFFUSION METHOD WITH CEFTAZIDIME AND CEFTRIAXONE AND COMBINED DISC METHOD WERE %85, %100, AND %23, AND IN ACINETOBACTER BAUMANNII ISOLATES, IT WAS REPORTED TO %100, %100, AND %7.7, RESPECTIVELY….

Cites

  • No record.
  • References

  • No record.
  • Related Journal Papers

  • No record.
  • Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops