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Title

MOLECULAR CHARACTERISTICS OF MACROLIDE RESISTANCE IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AND COAGULASE NEGATIVE STAPHYLOCOCCI

Writers

GHADERKHANI JALAL

Pages

 Start Page | End Page

Abstract

 BACKGROUND AND AIM: OVER THE PAST FEW DECADES A SIGNIFICANT INCREASE IN THE EMERGENCE OF ANTIBIOTIC-RESISTANT STRAINS OF METHICILLIN (MRSA) PARTICULARLY IN NOSOCOMIAL INFECTIONS HAS BEEN OBSERVED. THE AIM OF THIS STUDY IS TO IDENTIFY THE CHARACTERISTICS OF MACROLIDE RESISTANCE GENES AND LINCOZAMID RESISTANCE GENE AMONG METHICILLIN RESISTANCE STAPHYLOCOCCUS AUREUS AND COAGULASE NEGATIVE STAPHYLOCOCCI USING THE POLYMERASE CHAIN REACTION (PCR) TO FIND THE APPROPRIATIVE THERAPEUTIC METHOD.METHODS: ONE HUNDRED AND SEVENTY COAGULASE POSITIVE AND NEGATIVE STAPHYLOCOCCUS SAMPLES WERE COLLECTED FROM HOSPITALS IN THE WEST CITIES AND TEHRAN. ANTIBIOTIC RESISTANCES WERE EXAMINED BY PHENOTYPIC AND GENOTYPIC METHODS. PRESENCE OF ERMA, ERMB, ERMC, MSRA, LINA, MECA, AND FEMA GENES WERE INVESTIGATED BY PCR AND SUBSEQUENTLY DATA WERE ANALYZED USING SPSS…

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