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Title

MULTICALIBRATION METHOD FOR THE SIMULTANEOUS DETERMINATION OF PARACETAMOL AND VITAMIN B12 IN THE PHARMACEUTICAL PREPARATION

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Abstract

 BACKGROUND: PARACETAMOL (PAR) AND VITAMIN B12 (VB12) ARE WIDELY USED IN MANY PATIENTS PER DAY [1]. PAR, ALSO KNOWN AS ACETAMINOPHEN IS A WIDELY USED OVER-THE-COUNTER ANALGESIC (PAIN RELIEVER) AND ANTIPYRETIC (FEVER REDUCER) WHICH COMMONLY USED FOR THE RELIEF OF HEADACHES AND OTHER MINOR ACHES AND PAINS. VB12 ALSO CALLED COBALAMIN, IS ONE OF THE EIGHT B VITAMINS AND IS A WATER-SOLUBLE VITAMIN WITH A KEY ROLE IN THE NORMAL FUNCTIONING OF THE BRAIN AND NERVOUS SYSTEM, AND FOR THE FORMATION OF BLOOD.

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