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Title

PILOT-SCALE PRODUCTION OF LANSOPRAZOLE

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Abstract

 BACKGROUND: LANSOPRAZOLE (BENZIMIDAZOLE DERIVATIVES) IS AN IMPORTANT PROTON PUMP INHIBITOR THAT SUPPRESSES GASTRIC ACID SECRETION BY SPECIFIC INHIBITION OF THE GASTRIC H+, K+ ATPASE ENZYME SYSTEM. LANSOPRAZOLE IS EFFECTIVE IN THE TREATMENT OF VARIOUS PEPTIC DISEASE, INCLUDING GASTRIC AND DUODENAL ULCER AND REFLUX ESOPHAGITIS [1, 2]. …

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