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Title

VOLTAMMETRIC DETERMINATION OF CEFIXIME AT GLASSY CARBON ELECTRODE MODIFIED WITH 3-MERCAPTO-PROPYLTRIMETHOXYSILANE FUNCTIONALIZED CARBON NANOTUBES

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Abstract

 BACKGROUND: CEFIXIME (CEF) IS AN ORAL THIRD GENERATION CEPHALOSPORIN ANTIBIOTIC. IT IS USED FOR THE TREATMENT OF SUSCEPTIBLE INFECTIONS, INCLUDING GONORRHEA, OTITIS MEDIA, PHARYNGITIS, LOWER RESPIRATORY-TRACT INFECTIONS SUCH AS BRONCHITIS AND URINARY-TRACT INFECTIONS [1, 2]. TO DATE, NUMEROUS METHODS HAVE BEEN PROPOSED FOR THE ANALYSIS OF CEFIXIME USING DIFFERENT ANALYTICAL TECHNIQUES, SUCH AS: FLUORIMETRY [3], LIQUID CHROMATOGRAPHY (LC) –TANDEM MASS SPECTROMETRY [4], AND VOLTAMMETRY [5].

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