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Title

MULTILOCUS SEQUENCE ANALYSIS OF ANTIGENIC DETERMINANT GENES IN BORDETELLA PERTUSSIS VACCINAL AND ISOLATED STRAINS IN IRAN

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Abstract

 BACKGROUND AND AIM: PERTUSSIS IS AN INFECTIOUS RESPIRATORY DISEASE WHICH IS MOSTLY PREVALENT IN NEWBORN BABIES. STRAIN VARIATION MAY PLAY A ROLE IN THE PERSISTENCE OF B. PERTUSSIS AND WAS STUDIED BY SEQUENCING OF HOUSEKEEPING AND FIVE GENES CODING FOR SURFACE PROTEINS OF VACCINAL AND ISOLATED CLINICAL STRAINS TO EVALUATE THE GENOTYPE VARIATION LEVEL OF DOMESTICALLY DISTRIBUTED STRAINS AND CONFIRM THE CURRENT STATUS OF PERTUSSIS INCIDENCE.

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