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Information Seminar Paper

Title

ASSOCIATION OF EGFR GENE A-T POLYMORPHISM WITH RHEUMATOID ARTHRITIS IN IN SOUTHWEST IRAN

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Abstract

 INTRODUCTION: RHEUMATOID ARTHRITIS (RA) IS A CHRONIC INFLAMMATORY DISEASE, AFFECTING APPROXIMATELY UP TO 1% OF THE ADULT POPULATION WORLDWIDE. THE RHEUMATOID FIBROBLAST HAS A MANIFEST TUMOR-LIKE BEHAVIOR.SEVERAL CYTOKINE ACTIVATE THIS FIBROBLAST THROUGH TYROSINE KINASE GROWTH FACTOR RECEPTOR. EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) HAS A CRUCIAL ROLE IN THE RA DEVELOPMENT...

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