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Information Seminar Paper

Title

CLONING OF THE PROTEIN DISULFIDE ISOMERASE GENE IN PICHIA PASTORIS FOR EXPRESSION OPTIMIZATION OF SCFV

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Abstract

 INTRODUCTION: SCFV IS ONE OF THE MOST POPULAR FRAGMENTS FROM MONOCLONAL ANTIBODIES. ONE OF THE MOST IMPORTANT HOSTS FOR EXPRESSION OF THIS MOLECULE IS PICHIA PASTORIS. THERE ARE MANY METHODS FOR EXPRESSION OPTIMIZATION IN THIS HOST. AS THE POST-TRANSLATION, MODIFICATION IN ENDOPLASMIC RETICULUM. …

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