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Title

P262- INVESTIGATING THE EFFECTS OF VITAMIN C ON GROWTH AND PROLIFERATION OF LIMBAL EPITHELIAL STEM CELLS

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Abstract

 OBJECTIVE: LIMBAL EPITHELIAL STEM CELLS (LESC) HAVE A PIVOTAL ROLE IN THE MAINTENANCE AND ARRANGEMENT OF THE CORNEAL SURFACE. EPITHELIAL STEM CELLS OF THE CORNEA HAVE THE ABILITY OF SELF RENEWAL AND PROGENY PRODUCTION OF UNLIMITED DIFFERENTIATED CELLS. LESC CULTURE TECHNIQUES HAVE DRAWN A LOT OF ATTENTION IN REGENERATIVE MEDICINE. MANY CORNEAL DISORDERS SUCH AS LIMBAL STEM CELL DEFICIENCY (LSCD) CAN BE TREATED WITH LESC THERAPY. RECENT ADVANCES IN BIOTECHNOLOGY SUGGESTS THAT VITAMIN C CAN ENHANCE THE GENERATION OF HUMAN PLURIPOTENT STEM CELLS. IN THIS STUDY, WE TEND TO EVALUATE POSSIBLE PROLIFERATIVE EFFECTS OF VITAMIN C ON LESCS...

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