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Information Seminar Paper

Title

FINGOLIMOD REDUCES THE EXTENT OF DEMYELINATION AND INFLAMMATION FOLLOWING THE LOCAL ADMINISTRATION OF LYSOLECITHIN IN MICE

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Abstract

 INTRODUCTION: MULTIPLE SCLEROSIS (MS) IS THE MOST COMMON AUTOIMMUNE DISEASE, CHARACTERIZED BY INFILTRATION OF IMMUNE CELLS INTO THE CNS WHICH LEADS TO DEMYELINATION AND OLIGODENDROCYTE DEATH. FINGOLIMOD (FTY720), A SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATOR. THE EFFECT OF…

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