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Title

P253- SYSTEMIC TRANSPLANTATION OF HUMAN MESENCHYMAL STEM CELLS IN ANIMAL MODEL OF AUTISM: AMELIORATIVE EFFECTS IN MOTOR DISCOORDINATION

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Abstract

 ABSTRACT -----------------------------OBJECTIVE: MATERNAL VALPROIC ACID (VPA) EXPOSURE IS CAPABLE OF INDUCING EXPERIMENTAL AUTISM RESULTING IN NEUROBEHAVIORAL ABERRATIONS. AUTISM IS CHARACTERIZED WITH IMPAIRMENTS IN SOCIAL INTERACTIONS, AS WELL AS STEREOTYPED, REPETITIVE BEHAVIORS AND MOTOR BALANCE. WE INVESTIGATED THE INTRAVENOUS XENOTRANSPLANTATION OF HUMAN ADIPOSE DERIVED MESENCHYMAL STEM CELL (HA-MSC) ON AMELIORATION OF MOTOR DEFICITS IN A RAT MODEL OF AUTISM...

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