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Information Seminar Paper

Title

DIAGNOSIS OF HELICOBACTER PYLORI INFECTION IN CHILDREN AND ADULT BY SEROLOGICAL TEST AND STOOL ANTIGEN TEST

Writers

AZIZI GHOLAM REZA

Pages

 Start Page | End Page

Abstract

 BACKGROUND: HELICOBACTER PYLORI INFECTION CAUSES CHRONIC GASTRITIS THAT IS RELATED TO DUODENAL ULCER, GASTRIC ULCER, AND POSSIBLY GASTRIC ADENOCARCINOMA. NONINVASIVE DIAGNOSTIC TESTS CONSIST OF THE UREA BREATH TEST, SEROLOGY, AND STOOL ANTIGEN TESTING.SERODIAGNOSIS OF H.PYLORI INFECTION IS INACCURATE FOR CHILDREN. IN ORDER TO INVESTIGATE THE IMMUNE RESPONSE TO H.PYLORI IN CHILDREN AND ADULT, WE COMPARED ANTI-H PYLORI IGG AND IGA ANTIBODIES WITH H. PYLORI ANTIGEN (HPSA) IN THE STOOL.METHODS: SERUM AND STOOL SAMPLES WERE OBTAINED FROM 218 CHILDREN AND ADULT PATIENTS WITH CLINICAL SYMPTOM IN THE RANGE OF 4 TO 77 YEARS OLD. PAIRED RESULTS OF H. PYLORI SEROLOGY (IGG AND IGA) AND HPSA WERE ANALYZED BY ENZYME IMMUNOASSAY METHODS.

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