Seminar Paper

Paper Information

video

sound

Persian Version

View:

2,046

Download:

Cites:

Information Seminar Paper

Title

P233- EFFECTS OF A549-CONDITION MEDIUM ON MOUSE EMBRYONIC STEM CELLS DIFFERENTIATION INTO ALVEOLAR EPITHELIAL TYPE II CELLS

Pages

 Start Page | End Page

Abstract

 OBJECTIVE: A549 CELLS ARE ADENOCARCINOMIC HUMAN ALVEOLAR BASAL EPITHELIAL CELLS. THESE CELLS ARE RESPONSIBLE FOR THE DIFFUSION OF SOME SUBSTANCES, SUCH AS WATER AND ELECTROLYTES, ACROSS THE ALVEOLI OF LUNGS. A549 CELL LINE ARE WIDELY USED AS AN IN VITRO MODEL FOR A ALVEOLAR EPITHELIAL TYPE II (AETII) CELL MODEL FOR DRUG METABOLISM AND AS A TRANSFECTION HOST. THE MAIN FUNCTIONS OF AETII CELLS, INCLUDING THE SYNTHESIS AND SECRETION OF SURFACTANTS (A MIXTURE OF PROTEINS AND LIPIDS WHICH REDUCES SURFACE TENSION AND PREVENTING COLLAPSE OF THE ALVEOLUS), HYPERPLASIA IN REACTION TO ALVEOLAR EPITHELIAL INJURY AND ACT AS PROGENITOR CELLS FOR AETI CELLS (WHICH ARE ESSENTIAL FOR GAS EXCHANGE), THUS BEING ABLE TO RENEW THE ALVEOLAR EPITHELIUM. THE AIM OF THE STUDY WAS TO EVALUATE THE EFFECTS OF THE A549-CONDITION MEDIUM (A549-C.M) ON THE AETII CELLS DIFFERENTIATION FROM MOUSE EMBRYONIC STEM CELLS (MESCS)...

Cites

  • No record.
  • References

  • No record.
  • Related Journal Papers

  • No record.
  • Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops