Seminar Paper

Paper Information

video

sound

Persian Version

View:

660

Download:

Cites:

Information Seminar Paper

Title

P204- EXPRESSION ANALYSIS OF BORIS DURING RETINOIC ACID- INDUCED DIFFERENTIATION OF MOUSE EMBRYONAL CARCINOMA P19 CELLS

Writers

ARDESHIR M. | RUITENBURG W.

Pages

 Start Page | End Page

Abstract

 BACKGROUND/OBJECT: BORIS/CTCFL IS AN 11 ZINC FINGER (ZF) PROTEIN, WHICH IS THE PARALOG OF CTCF, A UBIQUITOUSLY EXPRESSED PROTEIN WITH DIVERSE ROLES IN GENE EXPRESSION AND CHROMATIN ORGANIZATION. SEVERAL STUDIES HAVE SHOWN THAT EXPRESSION OF BORIS IS RESTRICTED TO NORMAL ADULT TESTIS, PLURIPOTENT AND DIVERSE CANCER CELLS. THUS, IT IS KNOWN AS A CANCER-TESTIS (CT) GENE THAT HAS BEEN HYPOTHESIZED TO EXHIBIT ONCOGENIC PROPERTIES AND PROBABLY INVOLVE IN CANCER CELL PROLIFERATION. ON THE CONTRARY, OTHERS REPORTS HAVE SHOWN THAT ITS EXPRESSION IS MORE WIDESPREAD AND CAN BE DETECTED IN DIFFERENTIATED AND NORMAL SOMATIC CELLS; HENCE, IT MIGHT HAVE ROLES IN GENERAL CELLULAR FUNCTIONS. IN THE PRESENT STUDY, IN ORDER TO EXAMINE THESE CONTRADICTORY IDEAS...

Cites

  • No record.
  • References

  • No record.
  • Related Journal Papers

  • No record.
  • Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops