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Title

165- STUDY OF INVASION AND MATRIX METALLOPROTEINASES ACTIVITY IN GASTRIC CANCER STEM CELLS

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Abstract

 OBJECTIVE: METASTASIS IS THE SPREAD OF TUMOR CELLS FROM ONE ORGAN TO OTHER PLACES AND THE MAIN CAUSE OF CANCER-RELATED DEATH. MATRIX METALLOPROTEINASES PLAY AN IMPORTANT ROLE IN TUMOR MIGRATION AND ARE THE MAIN FACTORS IN METASTASIS. GASTRIC CANCER WAS THE SECOND MOST COMMON CANCER WORLDWIDE. DESPITE SURGERY AND CHEMOTHERAPY, MOST PATIENTS DIE OF METASTASIS AND RECURRENCE EVEN AFTER RIGOROUS THERAPY…

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