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Information Seminar Paper

Title

NECROPTOSIS IS INVOLVED IN THE HIPPOCAMPUS NEURON LOSS IN LIPOPOLYSACCHARIDE (LPS)-INJECTED RATS: A TIME-DEPENDENT STUDY

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Abstract

 INTRODUCTION: NECROPTOSIS AS NOVEL PROGRAMMED CELL DEATH CAN BE INVOLVED IN HIPPOCAMPUS NEURON LOSS IN ALZHEIMER DISEASE. RECEPTOR INTERACTING PROTEIN KINASES1 AND 3 (RIP1 AND RIP3) AND CASPASE 8 HAVE ESSENTIAL ROLE IN NECROPTOSIS SIGNALING-PATHWAY AND LPS CAN INITIATE NECROPTOSIS PATHWAY THROUGH TOLL-LIKE RECEPTOR4 AND PRODUCTION OF TNF-A. ...

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