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Title

KINETICS, EQUILIBRIUM AND THERMODYNAMIC STUDIES ON SULFASALAZINE ADSORPTION FROM DRINKING WATER BY CARBON NANOTUBES

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Abstract

 INTRODUCTION: GROUNDWATER CONTAMINATION BY PHARMACEUTICAL INGREDIENTS SUCH AS ANTIDEPRESSANTS, ANALGESICS, CONTRACEPTIVES, ANTIBIOTICS HAS BECOME AN ENVIRONMENTAL PROBLEM OF WIDESPREAD CONCERN [1, 2].ANTIBIOTICS ARE PROBABLY THE MOST SUCCESSFUL FAMILY OF DRUGS SO FAR DEVELOPED TO IMPROVE HUMAN HEALTH. SULFASALAZINE (5- ([P- (2-PYRIDYLSULFAMOYL) PHENYL] AZO SALICYLIC ACID, FIGURE 1) IS A SULFA DRUG THAT USES IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE, INCLUDING ULCERATIVE COLITIS AND BACTERIAL INFECTIONS WERE THE CAUSE OF RHEUMATOID ARTHRITIS. MANY METHODS HAVE BEEN ATTEMPTED FOR THE REMOVAL OF ANTIBIOTIC DRUGS FROM DIFFERENT WATER SOURCES. IN THE MAJORITY OF THE STUDIES INVOLVING SORPTIVE REMOVAL OF ANTIBIOTICS, ACTIVATED CARBON AND CARBON NANOTUBES HAS BEEN EMPLOYED AS A POTENTIAL SORBENT MATERIAL [3, 4].

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