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Title

THE EFFECTS OF GINGER SUPPLEMENTATION ON CARDIOVASCULAR RISKFACTORS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE: ARANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY

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 Start Page 211 | End Page 219

Abstract

 Introduction: Nonalcoholic fatty liver is avery common chronic liver disease that is caused by some factors such as insulinresistance, central obesity, type 2 diabetesmellitus and dyslipidemia. The beneficial effects of GINGER on metabolic disordershave been shown previously. The aim of this study was to investigate the effect ofginger supplementation on car diovascularrisk factors in patients with non-alcoholicfatty liver disease.Materials & methods: In this randomizedcontrolled clinical trial study, 50 patientswith NON-ALCOHOLIC FATTY LIVER disease participated in the intervention and place bogroups. For 12 weeks the intervention andplacebo groups received 2 gram of GINGERor placebo, respectively. Both groups were advised to follow a balanced diet and physical activity recommendations. Levels of INFLAMMATORY BIOMARKERS, lipid profile, fasting blood glucose, insulin and in sulinresistance were measured at the beginningand end of the study.Findings: GINGER supplementation reducedinflammatory biomarkers, fasting blood glucose, INSULIN RESISTANCE and triglyceridelevels more than placebo, but there were nosignificant changes in total cholesterol, HDL and LDL in each group.Discussion & conclusions: GINGER supplementation reduced levels of some cardiovascular risk factors in patients with NON-ALCOHOLIC FATTY LIVER disease.

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