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Endoscopic correction of vesicoureteral reflux in children




 Introduction: Dextranomer/hyaluronic (Dx/HA) acid is the only tissue-augmenting agent approved by the Food and Drug Administration (FDA) for the Vesicoureteral reflux (VUR) treatment. Objectives: We aimed to evaluate short-term outcomes of the Dx/HA in patients who had undergone Subureteric injection. Patients and Methods: In this study, 30 patients with VUR diagnosis who had indications for open surgery were enrolled in the study. Patients underwent subureteric Dx/HA injection. Additionally patients underwent a one-year follow up period, subsequently. Follow up included urine analysis, urine cultures and kidney and urinary tract ultrasonography study. Results: Of a total 30 patients, 8 patients (27%) were male and 22 patients (73%) were female. The mean age of patients was 25. 19 ± 0. 70 months. Postoperative VUR resolution was observed in 28 patients (93. 3%). Moreover, during one year follow up, Urinary tract infection (UTI) was not reported in patients. However, recurrent VUR was detected in 8 patients (27%) during ultrasonography follow up. Analysis showed no significant difference of recurrence in VUR between males and females (P = 0. 285) and VUR severity (P = 0. 1). There was a significant relationship between recurrent UTI history before intervention and VUR recurrence after Subureteric injection (P = 0. 007). Conclusion: Dx/HA acid Subureteric injection provides acceptable resolution rate among VUR patients, but its biodegradability causes VUR recurrence during one-year follow up.


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    APA: Copy

    Rahimi, Mohammad Mohsen, Nazarbaghi, Surena, VALIZADEH, ROHOLLAH, Fakour, Sanam, & Haghmoradi, Meisam. (2018). Endoscopic correction of vesicoureteral reflux in children. JOURNAL OF RENAL INJURY PREVENTION, 7(2), 89-93. SID.

    Vancouver: Copy

    Rahimi Mohammad Mohsen, Nazarbaghi Surena, VALIZADEH ROHOLLAH, Fakour Sanam, Haghmoradi Meisam. Endoscopic correction of vesicoureteral reflux in children. JOURNAL OF RENAL INJURY PREVENTION[Internet]. 2018;7(2):89-93. Available from:

    IEEE: Copy

    Mohammad Mohsen Rahimi, Surena Nazarbaghi, ROHOLLAH VALIZADEH, Sanam Fakour, and Meisam Haghmoradi, “Endoscopic correction of vesicoureteral reflux in children,” JOURNAL OF RENAL INJURY PREVENTION, vol. 7, no. 2, pp. 89–93, 2018, [Online]. Available:

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