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Information Journal Paper

Title

Polymorphism of insulin-like growth factor binding protein-3 (IGFBP-3) gene associated with growth traits in Cyprinus carpio

Pages

  172-176

Abstract

 The genetic polymorphism of insulin-like growth factor binding protein (IGFBP-3) and its association with the Growth traits namely condition factor, body weight, and total length were investigated in Common carp Cyprinus carpio using PCR-single strand conformation polymorphism (SSCP) technique. Caudal fin clips from 120 C. carpio, aging 5 months, were used in this study and a 330 bp DNA fragment was amplified from 5'-UTR of carp IGFBP-3. SSCP genotyping yielded seven different banding patterns namely A, B, C, D, E, F, and G with frequencies of 14. 16, 12. 5, 21. 67, 9. 17, 11. 67, 10. 0, and 20. 84, respectively. The obtained results showed a relatively high polymorphic behavior of 5'-UTR regulatory region of studied locus; therefore it shows the importance of this region in regulation of transcription of IGFBP-3 gene in carp. Marker-trait association showed significant relationships between the detected genotypes and condition factor (CF). IGFBP-3 gene polymorphism in joint with CF signifies relatively high genetic diversity and significant potential for marker-assisted selection in this species.

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    APA: Copy

    MEHRABI, Farzaneh, KHALESI, MOHAMMAD KAZEM, & FARHADI, AYOUB. (2015). Polymorphism of insulin-like growth factor binding protein-3 (IGFBP-3) gene associated with growth traits in Cyprinus carpio. IRANIAN JOURNAL OF ICHTHYOLOGY, 2(3), 172-176. SID. https://sid.ir/paper/718644/en

    Vancouver: Copy

    MEHRABI Farzaneh, KHALESI MOHAMMAD KAZEM, FARHADI AYOUB. Polymorphism of insulin-like growth factor binding protein-3 (IGFBP-3) gene associated with growth traits in Cyprinus carpio. IRANIAN JOURNAL OF ICHTHYOLOGY[Internet]. 2015;2(3):172-176. Available from: https://sid.ir/paper/718644/en

    IEEE: Copy

    Farzaneh MEHRABI, MOHAMMAD KAZEM KHALESI, and AYOUB FARHADI, “Polymorphism of insulin-like growth factor binding protein-3 (IGFBP-3) gene associated with growth traits in Cyprinus carpio,” IRANIAN JOURNAL OF ICHTHYOLOGY, vol. 2, no. 3, pp. 172–176, 2015, [Online]. Available: https://sid.ir/paper/718644/en

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