Journal Paper

Paper Information

video

sound

Persian Version

View:

11,450

Download:

5,343

Cites:

Information Journal Paper

Title

EFFECT OF VITAMIN E SUCCINATE ON INFLAMMATORY CYTOKINES INDUCED BY HIGH-INTENSITY INTERVAL TRAINING

Pages

 Start Page 0 | End Page 0

Keywords

HIGH-INTENSITY INTERVAL TRAINING (HIIT) 
INTERLEUKIN-6 (IL-6) 
TUMOR NECROSIS FACTOR ALPHA (TNF-α) 

Abstract

 Aim and Scope: The anti-inflammatory effect of vitamin E under moderate exercises has been evaluated. However, the effect of vitamin E succinate, which has more potent anti-inflammatory effect than other isomers of vitamin E has not been evaluated. Therefore, the aim of the present study was to evaluate the effects of vitamin E succinate on tumor necrosis factor alpha (TNF-a) and interleukin-6 (IL-6) production induced by high-intensity interval training (HIIT). Materials and Methods: In the present study, 24 rats were randomly divided into control (C), supplementation (S), HIIT, and HIIT+supplementation (HIIT+S) groups. HIIT training protocol on a treadmill (at a speed of 40–54 m/ min) and vitamin E succinate supplementation (60 mg/kg/day) was conducted for 6 weeks.Results: Serum IL-6 in the HIIT group significantly increased compared with the C group (350.42 ± 123.31 pg/mL vs 158.60 ± 41.96 pg/mL; P=0.002). Also, serum TNF-a concentrations significantly enhanced (718.15 ± 133.42 pg/mL vs 350.87 ± 64.93 pg/mL; P=0.001) in the HIIT group compared with the C group. Treatment of the training group with vitamin E numerically reduced IL-6 and TNF-a when compared with the HIIT group (217.31 ± 29.21 and 510.23 ± 217.88, respectively, P>0.05). However, no significant changes were observed in serum TNF-α (P=0.31) and IL-6 (P=0.52) concentrations in the HIIT+S group compared with the C group.Conclusion: HIIT-induced IL-6 and TNF-a decreased by administration of Vitamin E succinate.

Cites

  • No record.
  • References

  • No record.
  • Related Journal Papers

  • No record.
  • Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops