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Title

RECURRENT GALLBLADDER HYDROPS AND SCLEROSING CHOLANGITIS IN 11-YEAR-OLD MALE WITH HYPER IGM SYNDROME (LETTERS TO EDITOR)

Pages

 Start Page 705 | End Page 706

Abstract

 Hyper Immunoglobulin M (hyper IgM) is a rare immunodeficiency disorder first reported in 1961 [1], characterized by recurrent infections with low levels of serum IgA, IgG and IgE and normal to high levels of serum IgM [1]. Onset of manifestation of X-linked HIGM occurs in the 1st or 2nd year of life with recurrent pyogenic infections especially of upper and lower respiratory tract and diarrhea in 40% of the patients [1]. CRYPTOSPORIDIUM infections are a common cause of diarrhea in these patients complicated with hepatobiliary disease, which is severe and often fatal [1]. GALLBLADDER HYDROPS occurs in acutely severe ill children with inflammatory or non inflammatory conditions [2].

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