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Journal: IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY | Year:1383 | Volume:7 | Issue:1 | Start Page:71 | End Page:68

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Title

HUMAN CHORIONIC GONADOTROPIN AS A PREDICTOR OF OUTCOME IN ASSISTED REPRODUCTIVE TECHNOLOGY PREGNANCIES

Pages

 Start Page 71 | End Page 68

Abstract

 Objective: After assisted reproductive technology (ART) cycles, elevated serum hCG at 16 days after ovulation is used as an endocrine marker of pregnancy. The goal of this study is to determine whether serum hCG level obtained 16 days after ovulation is a reliable predictor of PREGNANCY OUTCOME.Material & Method: This is a retrospective study in women who have achieved pregnancy through ARJ treatment, in Montaserieh Hospital (IVF center). Analysis of data using logistic regression (stata) to predict a binary outcome: Ongoing pregnancy or miscarriage. Pregnancy was defined as progression to >20 weeks gestation. Miscarriage included spontaneous abortion, blighted ovum, or ectopic pregnancy.Results: Human chorionic gonadotropin (hCG) was found to be the main determinant of pregnancy; age had minor effects; whereas luteal support and treatment types were nonpredictive. Low hCG levels between 25-50 Iu/L were associated with a low probability of ongoing pregnancy (<25%), whereas levels of 200lU/ L and higher predict a >96% chance of ongoing pregnancy.Conclusions: A single serum hCG level 16 days after ovulation provides a useful predictor of PREGNANCY OUTCOME

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