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Information Journal Paper

Title

COMPARISON OF CAUDAL EPIDURAL ADMINISTRATION OF LIDOCAINE AND XYLAZINE TO XYLAZINE/KETAMINE COMBINATION IN DONKEY (EQUUS ASINUS)

Pages

  7-15

Abstract

 Objective- Evaulation of analgesic and sedative characteristics of XYLAZINE/ketamine combination for caudal EPIDURAL ANALGESIA in comparison with two routine agents in DONKEY. Design- Cross over study.Animals- Five healthy adult DONKEYs of both sexes with body weights ranging from 150-200 kg. Procedures- Three treatments [lidocaine HCl 2% (0.22 mg kg-1), XYLAZINE HCl 2% (0.17 mg kg- 1) and XYLAZINE HCl 2% (0.17 mg kg-1) combined with KETAMINE HCl 10% (1 mg kg-1)] were evaluated and animals received each of treatments randomly at one-week intervals. Cardiopulmonary parameters and rectal temperature were recorded before and every 15 minutes after epidural administration. The onset and duration of analgesia were evaluated every 5 minutes, using noxious stimulus (pin prick and pinch tests) on the skin of tail, perineum, anus and back thigh. Ataxia was assessed qualitatively between onset of anesthesia and return of sensation. The data were analyzed using analysis of variance followed by Dunnett's test; a Pvalue <0.05 was considered significant.Results- Administration of XYLAZINE along with KETAMINE resulted in more rapid onset and longer duration of analgesia (P<0.05), without any measurable cardiopulmonary side effects in comparison with the other treatments. However, severe ataxia was observed after the injection.Conclusion and Clinical Relevance- In a clinical point of view, despite early induction and longer duration of analgesia, this combination at these doses is not suitable for standing surgeries of hindquarters in DONKEY because there was unacceptable likelihood of recumbency.

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    APA: Copy

    SARAFZADEH REZAEI, F., REZAZADEH, F., & BEHFAR, M.. (2007). COMPARISON OF CAUDAL EPIDURAL ADMINISTRATION OF LIDOCAINE AND XYLAZINE TO XYLAZINE/KETAMINE COMBINATION IN DONKEY (EQUUS ASINUS). IRANIAN JOURNAL OF VETERINARY SURGERY (IJVS), 2(5), 7-15. SID. https://sid.ir/paper/555910/en

    Vancouver: Copy

    SARAFZADEH REZAEI F., REZAZADEH F., BEHFAR M.. COMPARISON OF CAUDAL EPIDURAL ADMINISTRATION OF LIDOCAINE AND XYLAZINE TO XYLAZINE/KETAMINE COMBINATION IN DONKEY (EQUUS ASINUS). IRANIAN JOURNAL OF VETERINARY SURGERY (IJVS)[Internet]. 2007;2(5):7-15. Available from: https://sid.ir/paper/555910/en

    IEEE: Copy

    F. SARAFZADEH REZAEI, F. REZAZADEH, and M. BEHFAR, “COMPARISON OF CAUDAL EPIDURAL ADMINISTRATION OF LIDOCAINE AND XYLAZINE TO XYLAZINE/KETAMINE COMBINATION IN DONKEY (EQUUS ASINUS),” IRANIAN JOURNAL OF VETERINARY SURGERY (IJVS), vol. 2, no. 5, pp. 7–15, 2007, [Online]. Available: https://sid.ir/paper/555910/en

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