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Title

AN INVESTIGATION OF THE RELATIONSHIP BETWEEN SERUM VITAMIN E STATUS AND CORONARY RISK FACTORS IN DYSLIPIDAEMIC PATIENTS

Pages

  206-215

Abstract

 Objective: VITAMIN E is a major lipid-soluble antioxidant. It has been demonstrated that VITAMIN E supplementation has a beneficial effect against CORONARY HEART DISEASE (CHD). This study to investigate the effects of coronary risk factors on serum VITAMIN E status in patients with DYSLIPIDAEMIA.Materials and Methods: This tertiary care hospital; case - control study was comprised 237 dyslipidaemic patients and 135 healthy individuals recruited from university and hospital employees. Serum VITAMIN E concentration was measured using high performance liquid chromatography (HPLC).Results: Compared to the healthy individuals, the dyslipidaemic patients had higher serum VITAMIN E (p<0.001), but serum VITAMIN E / total CHOLESTEROL ratio did not differ between patients and healthy controls (p>0.05). Serum VITAMIN E did not differ between subcategories of dyslipidaemic patients with and without coronary risk factors (p>0.05), but Serum VITAMIN E / total CHOLESTEROL ratio was higher in patients with established CORONARY HEART DISEASE (p<0.01), hypertriglyceridaemia (p<0.05) and METABOLIC SYNDROME (p<0.05). In the patients there was not a strong association between serum VITAMIN E or serum VITAMIN E / total CHOLESTEROL ratio and coronary risk factors except for the serum CHOLESTEROL.Conclusion: Serum VITAMIN E or VITAMIN E / total CHOLESTEROL ratio is not associated with the risk of CORONARY HEART DISEASE. Therefore, higher serum VITAMIN E or VITAMIN E / total CHOLESTEROL ratio doesn’t seem to have a preventive role against CORONARY HEART DISEASE.

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    • Cite

    APA: Copy

    GHAYOUR MOBARHAN, M., SAHEBKAR, A.H., STARKEY, B., LIVINGSTONE, C., WANG, T., LAMB, D., & FERNS, G.. (2008). AN INVESTIGATION OF THE RELATIONSHIP BETWEEN SERUM VITAMIN E STATUS AND CORONARY RISK FACTORS IN DYSLIPIDAEMIC PATIENTS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 10(4 (36)), 206-215. SID. https://sid.ir/paper/553913/en

    Vancouver: Copy

    GHAYOUR MOBARHAN M., SAHEBKAR A.H., STARKEY B., LIVINGSTONE C., WANG T., LAMB D., FERNS G.. AN INVESTIGATION OF THE RELATIONSHIP BETWEEN SERUM VITAMIN E STATUS AND CORONARY RISK FACTORS IN DYSLIPIDAEMIC PATIENTS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2008;10(4 (36)):206-215. Available from: https://sid.ir/paper/553913/en

    IEEE: Copy

    M. GHAYOUR MOBARHAN, A.H. SAHEBKAR, B. STARKEY, C. LIVINGSTONE, T. WANG, D. LAMB, and G. FERNS, “AN INVESTIGATION OF THE RELATIONSHIP BETWEEN SERUM VITAMIN E STATUS AND CORONARY RISK FACTORS IN DYSLIPIDAEMIC PATIENTS,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 10, no. 4 (36), pp. 206–215, 2008, [Online]. Available: https://sid.ir/paper/553913/en

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