Journal Paper

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Journal: JOURNAL OF CURRENT OPHTHALMOLOGY | Year:1382 | Volume:16 | Issue:3 | Start Page:38 | End Page:43

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Title

70 CASES OF CORNEAL GRAFTING AT HIGH RISK OF FAILURE; MASHAD: IMAM REZA HOSPITAL; 1991-2001

Pages

 Start Page 38 | End Page 43

Abstract

 Background: Knowledge of predisposing factors for ALLOGRAFT REJECTION or GRAFT FAILURE and their prevalence in penetrating keratoplasty (PK) is very important. Patients & Methods: In a descriptive study, 800 patient's records of PK were studied. 70 records with high-risk characteristics were selected. Incomplete records were omitted. Demographic data, including sex, age, predisposing factors, visual acuity and graft survival were analyzed. Results: Overall, 40 patients were male (57.1%), average age was 30.9y (1-74 years). The three most prevalent RISK FACTORs were multiple ALLOGRAFT REJECTIONs, corneal scar & neovascularization & chemical burn. The most common complication of surgery was ALLOGRAFT REJECTION (P<0.001). Visual acuity significantly increased after PK (P<0.001). Sex and age had no influence on results. Graft survival was 86%at 1 year, 69% at 3 years, 61% at 5 years and 27% at 10 years. The gravest results were for corneal scar & chemical burn. Discussion: Despite the presence of RISK FACTORs, penetrating keratoplasty had good results and increased visual acuity. Graft survival was in an acceptable range. CORNEAL GRAFT survival has increased with using new surgical techniques & supportive measures.    

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