video

sound

Persian Version

View:

144

Download:

0

Cites:

Information Journal Paper

Title

COMPARISON OF SERUM LEVELS OF SDF-1α CHEMOKINE IN PATIENTS WITH MYOCARDIAL INFARCTION AND HEALTHY PEOPLE

Pages

 Start Page 33 | End Page 42

Abstract

 Background and purpose: Cardiovascular diseases are the most common causes of death in Iran as well as in the world. SDF-1a, as an effective chemokine for decreasing inflammation and injury, plays a role in ANGIOGENESIS. This study compares and evaluates serum level of this chemokine in healthy people and those with AMI (Acute Myocardial Infarction) regarding age and gender.Materials and methods: This case-control study was conducted on two groups: 63 patients and 63 healthy participants (the relatives of other patients in other wards). Blood samples were taken in the first 24h of admission in both groups, whereas in the case group another blood sample was taken in the seventh day after admission. Data were collected through taking history of the patients and Paraclinic.Serum level of SDF-1a was also measured in the participants.Results: Among the participants enrolled in each group, 79.4% were males and 20.6% were females. In the AMI group, 80.95% were admitted due to their first heart attack and 63.5% had Q wave MI at the time of discharge. There was no significant difference in the serum concentration of SDF-1a between control (33.58) and case (33.71) groups in the blood sample taken in the first 24 hours (p>0.05). However, a significant difference was observed between that of the first day blood sample taken from the control group and the seventh day sample of the case group (132.12, p<0.05).Conclusion: Our study showed that the concentration of SDF-1a increased during the first week after AMI. Therefore, SDF1-a can be effective in AMI as an anti inflammatory and angiogenetic chemokine.

Cites

  • No record.
  • References

  • No record.
  • Related Journal Papers

    Related Seminar Papers

  • No record.
  • Related Plans

  • No record.
  • Recommended Workshops






    File Not Exists.