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Title

THE RELATIONSHIP BETWEEN XRCC1 AND XRCC6 GENES POLYMORPHISMS AND RENAL CELL CARCINOMA (LETTER)

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Abstract

 Dear Editor, POLYMORPHISMs of genes can cause a decrease in DNA repair capacity and disease susceptibility, as well (1, 2). The XRCC genes play a momentous role in comprehension processes of DNA repair in mammals, especially in doublestrand break (DSB) repair (3). Therefore, normal activity of XRCC genes is a major factor for cancer prevention. On the other hand, approximately, 84400 new patients of RENAL CELL CARCINOMA (RCC) are recognized by the Union of Europe.In addition, 34700 kidney cancer-related deaths happened in 2012 (4).

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