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Title

BRUCELLOSIS VACCINES: AN OVERVIEW

Writers

 HASANJANI ROUSHAN MOHAMMAD REZA | KAZEMI SOHRAB | FALLAH ROSTAMI FATEMEH | EBRAHIMPOUR SOHEIL

Pages

 Start Page 118 | End Page 124

Abstract

 Objective: BRUCELLOSIS is considered as an important zoonotic and worldwide infection with more than half of million human cases, which it occurs more and more in animals like as wild and live stocks. Sheep, cattle, and goats are animal samples that listed. Symptoms of this disease in human are consisted of: undulant fever, back pains, faint, spondylitis, arthritis and orchitis. This infection causes ABORTION in livestock, and this point is one of the important economic losses. Reduction in milk production is another problem in this disease too.Materials and Methods: This study is conducted by reviewing of the literatures, which are related to this concern, and also visiting PubMed, ISI and other websites.Results: We must pay heed that most ZOONOSES are maintained in the animal reservoir. These diseases, such as leptospirosis, Q-fever, BRUCELLOSIS etc. which among them BRUCELLOSIS can transfer to human via close contact with infected animals or consumption of unpasteurized dairy. Therefore, eradication of this infection in human population is depended on omission of that in possible methods among animals reservoir. Such methods are like test-slaughter and vaccination of livestock. Hence, vaccination is not alone method for controlling, but it is probably economic one.Conclusion: Nowadays a vaccine which is effective for this disease control in human is not available. Of course presented some different VACCINES for this infection in livestock that cleave live attenuated, killed bacteria and sub unit. Therefore, for eradication of this disease some VACCINES with more effectiveness protection mid fewer side effects are necessary.

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