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Title

DIETARY PATTERNS AND DEPRESSION DISORDERS IN IRANIAN ADULTS

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 Start Page 129 | End Page 129

Abstract

 Background: DEPRESSION is globally prevalent both in developed and developing countries. Limited data are available in relation to DIETARY PATTERNs and DEPRESSION disorders. We are aware of no report in non-western nations especially the Middle-eastern populations, where the dietary intakes are highly different from other parts of the world. This study examined the relationship between major DIETARY PATTERNs derived from PRINCIPLE COMPONENT ANALYSIS and prevalence of DEPRESSION in a large sample of Iranian adults.Methods: This cross-sectional study included 4763 Iranian general adult population aged 20-55 years. Thirty three food items were entered in to the PRINCIPLE COMPONENT ANALYSIS to identify DIETARY PATTERNs. Examination of current major depressive disorder was assessed with the Iranian validated version of Hospital Anxiety and DEPRESSION Scale (HADS) and 12 item general health questionnaires (GHQ-12) was used to measure psychological symptoms. To find the association between DIETARY PATTERNs and psychological disorders, we used logistic regression in different models with adjusting for age and then for sex marital status, education, physical activity, chronic diseases, smoking and antidepressant use and energy intake (kcal/d). Further adjustments for BMI were done in the last model also. To assess the overall trend of odds ratios across increasing quartiles of DIETARY PATTERN scores, we treated the quartile categories as an ordinal variable in the analyses. All analyses were performed using SPSS software (version 19.0; SPSS Inc, Chicago IL). P values were considered significant at<0.05.Results: Mean age of study population was 36.4±8.0 years. Prevalence of DEPRESSION, anxiety and psychological distress was 10.6 (men: 7.0% and women: 13.5%), 5.7 (men: 4.4% and women: 6.8%) and 23.3% (men: 18.4% and women: 26.5%), respectively. After adjustment for potential confounders, lacto-vegetarian DIETARY PATTERN was protectively associated with DEPRESSION in women (OR: 65; 95% CI: 0.46-0.91). In addition, traditional DIETARY PATTERN was positively associated with DEPRESSION (1.42; 1.01-1.99) in women. Western DIETARY PATTERN was positively associated with DEPRESSION in men (OR: 1.73; CI: 1.07-2.86). These associations persisted in multivariate models adjusting for a wide range of possible confounding variables.Conclusion: In our study some DIETARY PATTERN had significant association with DEPRESSION but further prospective studies are requires finding out the direction of the relationships. As dietary intake unlike many other risk factors, is a modifiable environmental condition, this finding could provide evidence-based health care strategy to prevent mental illness.

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