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Title

SHORT COMMUNICATION: DIFFERENTIATION BETWEEN VIRAL EXANTHEMA AND ALLERGIC EXANTHEMA BY IFN-γ AND IL-4 ASSAY

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 Start Page 35 | End Page 37

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Abstract

 Macular and maculo-papular skin reactions are frequent events in viral infections as well as in allergies (1,2,3). Their histology and clinical morphology is often similar and clinical diagnosis of rash is often difficult and misdiagnosis is not rare, specially in failure to detect virus specific antibodies of the IgM class.(4,5,6,7,8). Measles, rubella and parvovirus B19 are the most important childhood exanthematic disease, but some other viruses (enteroviruses, HHV-6, EBV, etc) can cause exanthema(9) that diagnosis of each of them separately, requires spending lots of time and money. On the other hand, allergies are another important cause of exanthema and differentiation between viral exanthema and allergic exanthema can be difficult sometimes (10).

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