Journal Paper

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Journal: HEPATITIS MONTHLY | Year:0 | Volume:11 | Issue:4 (33) | Start Page:263 | End Page:268

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Title

RISK FACTORS OF HEPATITIS B VIRUS INFECTION IN TURKEY: A POPULATION-BASED, CASE-CONTROL STUDY

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 Start Page 263 | End Page 268

Abstract

 Background: Although the World Health Organization (WHO) classifies Turkey as a country with a moderate-high prevalence of HEPATITIS B VIRUS (HBV) infection, there is little data on HBV TRANSMISSION in this country.Objectives: To identify RISK FACTORs for HBV infection, we performed a retrospective case-control study between January 2007 and December 2009.Patients and Methods: Acute HBV patients and population controls were selected, and data from these groups were analyzed by logistic regression. method.Results: The study included 129 patients with acute HBV infection and 219 controls. Hemodialysis (OR: 8.2, 95% CI: 4.17-16.61, p<0.05), having an HBsAg (+) spouse (OR: 4.3, 95% CI: 2.17-8.53, p<0.05), living with an HBsAg (+) parent (s) (OR: 3.25, 95% CI: 1.73-6.12, p<0.05), and being male (OR: 1.34, 95% CI: 0.82-2.21, p<0.05) were independent RISK FACTORs that were potentially associated with HBV infection. More than one-third of female patients had a significantly higher risk (34.5% vs.13.5%, p<0.05) of acquiring HBV from their sexual partners. Hemodialysis was the most frequent RISK FACTOR (46.9% vs.20%, x²=10.45, p<0.05) for patients aged over 31 years, and living with HBsAg (+) parents was a significantly higher RISK FACTOR (28.8% vs.10.2%, x²=6.15, p<0.05) that is more likely to lead to HBVin patients aged under 30 years.Conclusions: This study suggests that persons in Turkey who undergo hemodialysis are at high risk for acquiring HBV. Having an HBsAg (+) spouse (sexual TRANSMISSION) or living with HBsAg (+) parents (household TRANSMISSION) are significant RISK FACTORs for HBV TRANSMISSION. Vaccination appears to be better preventive method against the spread of HBV.

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